Peak Human Labs

In this video, Dr Goel and Neeraj Jain discusses the results of a new trial examining the impact of caloric restriction on aging. 📚 PURCHASE DR. SANJEEV GOEL'S BOOK "The Top 10 Must Do Peak Human Biohacks of 2023"📚 → iBooks: https://books.apple.com/ca/book/top-10-must-do-peak-human-biohacks-of-2023/id6448680046 → Kobo: https://www.kobo.com/ca/en/ebook/the-top-10-must-do-peak-human-biohacks-of-2023 → Amazon - https://www.amazon.com/dp/B0C1J2N1YF ******************** Visit our website: https://peakhuman.ca/?v=3e8d115eb4b3 Shop here: https://peakhuman.ca/shop/ SUBSCRIBE TODAY: https://bit.ly/PeakHumanLabs Effect of long-term caloric restriction on DNA methylation measures of biological aging in healthy adults from the CALERIE trial https://www.nature.com/articles/s43587-022-00357-y ****************** TIMESTAMP 0:00 - Introduction 1:30 - Aging Theories and Background 3:15 - Caloric Restriction Mechanisms 5:45 - Previous Studies on Caloric Restriction 8:10 - New Study Results Overview 10:30 - Study Methodology & Participants 12:50 - Caloric Restriction Effects on Aging 15:20 - Side Effects and Considerations 17:40 - Practical Implications & Recommendations 20:00 - Future Research Directions 21:30 - Conclusion & Final Thoughts #caloricrestriction #aging #calorie

In this video, Dr. Goel dives into the science behind spermidine, a lesser-known compound found in various foods and produced by gut bacteria. Order Fasting Pro at https://peakhuman.ca/product/fasting-pro/?v=3e8d115eb4b3 - Only supplement available on the market with 10 grams of Spermidine per serving. https://youtube.com/live/oSFIba0FznA 📚 PURCHASE DR. SANJEEV GOEL'S BOOK "The Top 10 Must Do Peak Human Biohacks of 2023"📚 → iBooks: https://books.apple.com/ca/book/top-10-must-do-peak-human-biohacks-of-2023/id6448680046 → Kobo: https://www.kobo.com/ca/en/ebook/the-top-10-must-do-peak-human-biohacks-of-2023 → Amazon - https://www.amazon.com/dp/B0C1J2N1YF ******************** Visit our website: https://peakhuman.ca/?v=3e8d115eb4b3 Shop here: https://peakhuman.ca/shop/ SUBSCRIBE TODAY: https://bit.ly/PeakHumanLabs Discover the potential of spermidine as an anti-aging supplement. Learn how spermidine promotes autophagy, a process that aids in clearing out damaged cells and byproducts, contributing to healthier living and longevity. Explore the benefits of spermidine, including improved heart function, decreased blood pressure, neural protection, and more. Discover how to integrate spermidine into your routine and the exclusive offering of Peak Human's Fasting Pro supplement, packed with a generous 10 milligrams of spermidine. Stay ahead in the world of anti-aging with this insightful episode! Subscribe to our YouTube channel for more informative content and join the discussion in the comments below. ****************** TIMESTAMP 0:00 - Intro 0:27 - Introduction to Spermidine 0:39 - Spermidine's Research Background 1:00 - Spermidine's Protective Effects 1:19 - Caloric Restriction and Longevity 1:49 - Caloric Restriction Mimetics (CRMs) 2:03 - Spermidine as a CRM 2:17 - Spermidine's Role in Autophagy 2:29 - Autophagy and Its Importance 2:45 - Fasting and Autophagy 2:57 - Autophagy's Role in Healthy Living 3:12 - Spermidine's Positive Effects in Animals 3:34 - Spermidine's Effects on Heart Function 3:58 - Spermidine's Potential Anti-Cancer Properties 4:19 - Research on Spermidine in Rodents 4:38 - Spermidine's Benefits in Humans 4:59 - Improved Cardiovascular Health in Humans 5:15 - Spermidine's Safety and Availability 5:35 - Peak Human's Fasting Pro Product 5:57 - Encouragement to Do Further Research 6:07 - Conclusion #SpermidineBenefits #AntiAgingSupplements #HealthyLongevity

In this video, join Dr. Goel as he delves into the fascinating world of hair loss, hair growth, and evidence-based treatments. 📚 PURCHASE DR. SANJEEV GOEL'S BOOK "The Top 10 Must Do Peak Human Biohacks of 2023"📚 → iBooks: https://books.apple.com/ca/book/top-10-must-do-peak-human-biohacks-of-2023/id6448680046 → Kobo: https://www.kobo.com/ca/en/ebook/the-top-10-must-do-peak-human-biohacks-of-2023 → Amazon - https://www.amazon.com/dp/B0C1J2N1YF ******************** Visit our website: https://peakhuman.ca/?v=3e8d115eb4b3 Shop here: https://peakhuman.ca/shop/ SUBSCRIBE TODAY: https://bit.ly/PeakHumanLabs Dr. Goel discusses the various causes of hair loss, including androgenic alopecia, trauma, infections, and autoimmune conditions. He explains the role of DHT in male and female pattern baldness, shedding light on the biochemical processes that lead to hair follicle deterioration. Discover the importance of the hair cycle and learn about proven treatments, such as DHT blockers like finasteride and dutasteride, low-level light therapy, topical and oral minoxidil, platelet-rich plasma (PRP), peptides like GHK copper, and more. If you're curious about maintaining healthy hair or looking for effective solutions, this episode is a must-watch. Subscribe for more informative content on hair health and related topics! ****************** TIMESTAMP 0:00 - Intro 0:20 - Discussion of hair loss causes 0:32 - Androgenic alopecia (AGA) explanation 0:46 - Other causes of hair loss 1:15 - Alopecia areata and its distressing effects 1:54 - Focus on androgenic alopecia 2:08 - Role of androgens and DHT in hair loss 2:27 - Biochemical basis of androgenic alopecia 3:18 - Male pattern baldness patterns 4:00 - Hair follicle growth cycle explanation 4:29 - Strategies to protect hair follicles 4:55 - Five Alpha reductase blockers (e.g., finasteride, dutasteride) 6:03 - Minoxidil (Rogaine) treatment and its limitations 7:04 - Oral minoxidil as an alternative 8:05 - Low-level light therapy for hair rejuvenation 9:25 - Use of PRP (platelet-rich plasma) for hair growth 10:25 - Potential of exosomes in hair treatment 10:35 - Mention of peptides for hair stimulation 11:46 - Conclusion #HairLossSolutions #HealthyHairGrowth #ScienceOfHairCare

In this video, Dr. Goel discusses the latest groundbreaking study on a new medication called "donanemab," a monoclonal antibody targeting amyloid and Tau proteins. Learn more about Donanemab → https://jamanetwork.com/journals/jama/fullarticle/2807533?guestAccessKey=855d51a0-c676-46f8-8bb3-1ecaa471d5eb&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=071723%20[jamanetwork.com] 📚 PURCHASE DR. SANJEEV GOEL'S BOOK "The Top 10 Must Do Peak Human Biohacks of 2023"📚 → iBooks: https://books.apple.com/ca/book/top-10-must-do-peak-human-biohacks-of-2023/id6448680046 → Kobo: https://www.kobo.com/ca/en/ebook/the-top-10-must-do-peak-human-biohacks-of-2023 → Amazon - https://www.amazon.com/dp/B0C1J2N1YF ******************** Visit our website: https://peakhuman.ca/?v=3e8d115eb4b3 Shop here: https://peakhuman.ca/shop/ SUBSCRIBE TODAY: https://bit.ly/PeakHumanLabs Published in Jama on July 17th, this randomized clinical trial involved over 1700 patients with early Alzheimer's disease and showed promising results. The medication demonstrated a significant decrease in disease progression, with patients experiencing up to a 30% reduction in symptoms over an 18-month period. Join Dr. Goyle as he dives into the key points of the study and highlights the potential impact of this new treatment. Don't miss out—subscribe to our channel for more informative updates on the battle against Alzheimer's. Leave your comments and thoughts below! Together, we can make a difference in the fight against this devastating disease. ****************** TIMESTAMP 0:00 - Intro 0:27 - Highlighting a new study on Alzheimer's medication 0:48 - Introducing the medication "donanemab" 0:53 - Medication targets amyloid and Tau proteins 0:59 - Overview of the study and its scope 1:01 - Key points of the study explained 1:20 - Significant progression decrease with the medication 1:31 - Approximately 30% reduction in disease progression 1:42 - Emphasizing the effectiveness of the medication 1:58 - Encouraging audience engagement and subscriptions 2:05 - Conclusion #Donanemab #NewAlzheimersMedication #MedicalBreakthroughs

In this video, we delve into the fascinating world of biological age testing. Biologic Age Test → http://www.peakhuman.ca/ 📚 PURCHASE DR. SANJEEV GOEL'S BOOK "The Top 10 Must Do Peak Human Biohacks of 2023"📚 → iBooks: https://books.apple.com/ca/book/top-10-must-do-peak-human-biohacks-of-2023/id6448680046 → Kobo: https://www.kobo.com/ca/en/ebook/the-top-10-must-do-peak-human-biohacks-of-2023 → Amazon - https://www.amazon.com/dp/B0C1J2N1YF ******************** Visit our website: https://peakhuman.ca/?v=3e8d115eb4b3 Shop here: https://peakhuman.ca/shop/ SUBSCRIBE TODAY: https://bit.ly/PeakHumanLabs Join us as we uncover the concept of biological age, which may differ from our chronological age, and its implications for longevity medicine. Discover how various lifestyle factors can influence the aging process and learn about cutting-edge techniques that can measure biological age. We explore the science behind DNA marks and epigenetics, which allow us to predict disease risks and track aging patterns. Join us on this informative journey and gain insights into optimizing your health and well-being. Don't forget to like, subscribe, and share your thoughts in the comments section! ****************** TIMESTAMP 0:00 - Introduction 2:02 - Explaining the science behind biological age testing and DNA marks 4:01 - Different types of clocks measuring biologic age and their predictive capabilities 6:05 - Epigenetics and how DNA marks affect gene expression 7:55 - Importance of biological age testing and its potential as a wake-up call 9:23 - Personal experience with biological age testing and the potential for improvement 9:44 - Closing remarks #BiologicalAgeTesting #AgingScience #LongevityMedicine

In this video, we delve into the fascinating topic of saunas and their potential health benefits, particularly their impact on Alzheimer's disease. Learn more about Hot and Cold Therapy → https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437631/ → https://www.alzdiscovery.org/cognitive-vitality/blog/can-using-the-sauna-reduce-risk-for-alzheimers-disease 📚 PURCHASE DR. SANJEEV GOEL'S BOOK "The Top 10 Must Do Peak Human Biohacks of 2023"📚 → iBooks: https://books.apple.com/ca/book/top-10-must-do-peak-human-biohacks-of-2023/id6448680046 → Kobo: https://www.kobo.com/ca/en/ebook/the-top-10-must-do-peak-human-biohacks-of-2023 → Amazon - https://www.amazon.com/dp/B0C1J2N1YF ******************** Visit our website: https://peakhuman.ca/?v=3e8d115eb4b3 Shop here: https://peakhuman.ca/shop/ SUBSCRIBE TODAY: https://bit.ly/PeakHumanLabs Join us as we explore the findings of observational studies conducted over the course of several years, shedding light on the association between sauna use and a reduced risk of Alzheimer's. We discuss the sauna experience, optimal frequency and duration, temperature range, and the benefits of sweating. Additionally, we touch upon the intriguing connection between cold therapy and Alzheimer's prevention. Discover how stressors like saunas and cold exposure can positively influence your body's metabolism, energy levels, and overall well-being. Stay up-to-date with the latest research on Alzheimer's and join us on this journey toward better health. ****************** TIMESTAMP 0:00 - Introduction 0:14 - Saunas and their impact on Alzheimer's 1:16 - What is a sauna? 1:39 - Duration and frequency of sauna sessions 2:04 - Health benefits of saunas, including sweating and toxin elimination 3:08 - Observational study on sauna frequency and Alzheimer's risk reduction 4:00 - Another study on sauna frequency and dementia risk reduction 6:00 - Optimal sauna frequency and duration 6:32 - Benefits of saunas for blood pressure and inflammation reduction 7:10 - Weight loss and other potential benefits of saunas 8:00 - Cold therapy and its potential benefits for Alzheimer's 9:00 - Saunas and cold therapy as stressors for the body 10:04 - The importance of stimulating the body through sauna and cold exposure 10:32 - Conclusion #AlzheimersTherapy #HotAndColdTreatment #AlzheimersPrevention

In this video, join Carmelia Ray and Dr. Sanjeev Goel as he provides an update on the latest research and findings related to Alzheimer's disease. 📚 PURCHASE DR. SANJEEV GOEL'S BOOK "The Top 10 Must Do Peak Human Biohacks of 2023"📚 → iBooks: https://books.apple.com/ca/book/top-10-must-do-peak-human-biohacks-of-2023/id6448680046 → Kobo: https://www.kobo.com/ca/en/ebook/the-top-10-must-do-peak-human-biohacks-of-2023 → Amazon - https://www.amazon.com/dp/B0C1J2N1YF ******************** Visit our website: https://peakhuman.ca/?v=3e8d115eb4b3 Shop here: https://peakhuman.ca/shop/ SUBSCRIBE TODAY: https://bit.ly/PeakHumanLabs The discussion revolves around the connection between the gut microbiome and Alzheimer's risk. Two recent studies are highlighted, demonstrating that individuals at higher risk for Alzheimer's exhibit different gut bacteria even years before the onset of symptoms. The conversation explores the potential role of gut bacteria in releasing molecules that contribute to the buildup of amyloid proteins in the brain. While the exact relationship between gut bacteria and Alzheimer's is still being studied, the significance of maintaining a healthy gut microbiome for overall health is emphasized. The video also mentions the availability of genetic tests and early detection methods to assess the risk of Alzheimer's. Dr. Sanjeev shares his personal experience visiting the Toronto Memory Program and his intention to undergo a PET scan to detect amyloid deposits in his brain. The importance of being proactive and seeking preventive measures is highlighted, encouraging viewers to take control of their Alzheimer's journey. Don't miss out on this valuable information! Subscribe, like, and leave your questions and comments to join the fight against Alzheimer's. ****************** TIMESTAMP 0:00 - Introduction 0:15 - Update on Gut Microbiome Research 2:00 - Association between Gut Bacteria and Alzheimer's Risk 3:12 - Testing and Identifying Changes in Gut Bacteria 4:12 - Importance of Maintaining a Healthy Gut 5:27 - Microbiome Testing and Functional Medicine Practitioners 7:02 - Dr. Sanjeev's Visit to the Toronto Memory Program 8:49 - The Importance of Proactive Measures 9:17 - PET Scan and Amyloid Deposits in the Brain 10:06 - Closing Remarks #AlzheimersAwareness #ResearchUpdate #GutBrainConnection

In this video, join us as we explore the fascinating world of exosomes, the latest craze in regenerative medicine. Learn more of the EXOSOMES here: https://www.nature.com/articles/s41413-020-0100-9 📚 PURCHASE DR. SANJEEV GOEL'S BOOK "The Top 10 Must Do Peak Human Biohacks of 2023"📚 → iBooks: https://books.apple.com/ca/book/top-10-must-do-peak-human-biohacks-of-2023/id6448680046 → Kobo: https://www.kobo.com/ca/en/ebook/the-top-10-must-do-peak-human-biohacks-of-2023 → Amazon - https://www.amazon.com/dp/B0C1J2N1YF ******************** Visit our website: https://peakhuman.ca/?v=3e8d115eb4b3 Shop here: https://peakhuman.ca/shop/ SUBSCRIBE TODAY: https://bit.ly/PeakHumanLabs Exosomes are like messenger signals, tiny packets of molecules found within stem cells, allowing cells to communicate and send regenerative messages to each other. Discover how exosomes have the potential to treat various diseases, improve skin quality, enhance hair growth, and even aid in conditions like arthritis and cardiac regeneration. While not yet FDA-approved, these research-based therapies are showing promising results. Learn more about the potential of exosomes and other cutting-edge biohacks by grabbing a copy of our book, available on Amazon, Kobo, and iBooks. Subscribe to our channel for more exciting episodes and don't hesitate to leave your questions in the comments below. Stay tuned for next week's episode. ****************** TIMESTAMP 0:00 - Introduction 0:14 - Top 10 Must-Do Peak Human Biohacks of 2023 0:31 - Chapter Three: Exosomes - The Regenerative Medicine Bullet 1:10 - Explaining Exosomes and their role as messenger signals 1:56 - Potential of exosomes for repairing and regenerating cells 3:05 - FDA-approved topical use for improving skin quality 3:57 - Research on injecting exosomes for hair growth and arthritis 4:46 - Promising results for burns and other regenerative treatments 5:17 - Availability and consultation with a regenerative physician 6:06 - Conclusion #Exosomes #RegenerativeMedicine #Biohacks

In this video, join Dr. Sanjeev and Carmelia Ray as they dive into the fascinating world of circadian rhythms. Circadian Wellness and Health - https://nigms.nih.gov/education/fact-sheets/Pages/circadian-rhythms.aspx 📚 PURCHASE DR. SANJEEV GOEL'S BOOK "The Top 10 Must Do Peak Human Biohacks of 2023"📚 → iBooks: https://books.apple.com/ca/book/top-10-must-do-peak-human-biohacks-of-2023/id6448680046 → Kobo: https://www.kobo.com/ca/en/ebook/the-top-10-must-do-peak-human-biohacks-of-2023 → Amazon - https://www.amazon.com/dp/B0C1J2N1YF ******************** Explaining the concept of circadian rhythms as biological rhythms based on the daily cycle, Dr. Goel sheds light on the crucial role of light in regulating our body's 24-hour clock. From the impact of light on our suprachiasmatic nucleus to the importance of living in harmony with our natural rhythms, this video provides valuable insights into maintaining a healthy body. Discover the significance of monitoring your body rhythm, the role of routine, and the effects of jet lag and travel on our circadian rhythms. Dr. Goel also touches upon other rhythms such as monthly and seasonal cycles and shares a recommended wearable device for tracking circadian rhythms. Stay tuned to learn how you can be more intentional about your body's rhythm for optimal health and well-being. ****************** Visit our website: https://peakhuman.ca/?v=3e8d115eb4b3 Shop here: https://peakhuman.ca/shop/ SUBSCRIBE TODAY: https://bit.ly/PeakHumanLabs TIMESTAMP 0:00 - Introduction 2:09 - Monitoring body rhythm and maintaining good rhythm 3:43 - Impact of travel and jet lag on rhythm 5:48 - Importance of routine and avoiding disruptions 7:28 - Use of wearable technology to monitor rhythm 7:53 - Discussion on monthly and seasonal rhythms 11:08 - Conclusion and final thoughts #CircadianRhythm #ImpactOnHealth #HealthandWellness

In this video, Dr. Sanjeev and Carmelia Ray discuss the impact of social media on mental health. Some stats on the use of social media https://bit.ly/3NKF5ic Research paper on the effect of the Facebook rollout: https://bit.ly/3XQj5ak ******************** 📚 PURCHASE DR. SANJEEV GOEL'S BOOK "The Top 10 Must Do Peak Human Biohacks of 2023"📚 → iBooks: https://books.apple.com/ca/book/top-10-must-do-peak-human-biohacks-of-2023/id6448680046 → Kobo: https://www.kobo.com/ca/en/ebook/the-top-10-must-do-peak-human-biohacks-of-2023 → Amazon - https://www.amazon.com/dp/B0C1J2N1YF ******************** They mention the increase in social media use and the negative effects it can have, such as anxiety and depression. They also talk about a study that found a decrease in depression among those who limited their social media use to 10 minutes a day. They discuss the comparison syndrome and the unrealistic portrayal of lives on social media. They touch on dopamine and its role in the reward system, as well as the release of cortisol in response to chronic stress. They suggest cutting down on social media use and taking control of what content you see. They also mention the concept of "techno fasting" as a way to take breaks from technology. ****************** Visit our website: https://peakhuman.ca/?v=3e8d115eb4b3 Shop here: https://peakhuman.ca/shop/ SUBSCRIBE TODAY: https://bit.ly/PeakHumanLabs TIMESTAMP 0:00 - Introduction 0:15 - Discussion about the importance of the topic 1:03 - Stats on the use of social media and its impact 2:05 - Mention of increased anxiety, depression, and suicide rates 2:28 - Study by Melissa Hunt on the impact of social media use 3:35 - Effects of reducing social media use on depression and FOMO 4:27 - Discussion on comparison syndrome and its effects 5:09 - Recommendations for dealing with comparison on social media 6:07 - Explanation of dopamine and its role in social media addiction 7:02 - Question about the involvement of oxytocin 7:38 - Clarification on dopamine's role and addictive tendencies 9:01 - Study on the rollout of Facebook and its impact on mental health 10:07 - Mention of other social media platforms and their potential effects 10:30 - Discussion on increased cortisol levels and its consequences 11:11 - Personal experience with social media and the need for breaks 12:43 - Proposal for techno fasting as a solution 14:49 - Conclusion #MentalHealthMatters #SocialMediaImpact #DigitalWellness

In this video, we dive into the fascinating world of vitamin K2 and its impact on our health. 📚 PURCHASE DR. SANJEEV GOEL'S BOOK "The Top 10 Must Do Peak Human Biohacks of 2023"📚 → iBooks: https://books.apple.com/ca/book/top-10-must-do-peak-human-biohacks-of-2023/id6448680046 → Kobo: https://www.kobo.com/ca/en/ebook/the-top-10-must-do-peak-human-biohacks-of-2023 → Amazon - https://www.amazon.com/dp/B0C1J2N1YF ******************** Discover the surprising health benefits of this vitamin beyond its association with bone health. Learn how Vitamin K27, found naturally in fermented foods, can potentially reduce atherosclerosis, the leading cause of heart attacks and heart disease. Dr. Sanjeev explains the mechanism behind this vital nutrient and its role in removing plaque buildup from the arteries. Find out how Vitamin K27 can be a game-changer in your cardiovascular health journey. Don't miss this fascinating episode and grab a copy of Dr. Sanjeev's book, "The 10 Must-Do Biohacks of 2023," available on Amazon, iBooks, and Kobo. Take the first step towards a healthier heart and brush your veins with Vitamin K27! ****************** Visit our website: https://peakhuman.ca/?v=3e8d115eb4b3 Shop here: https://peakhuman.ca/shop/ SUBSCRIBE TODAY: https://bit.ly/PeakHumanLabs TIMESTAMP 0:00 - Introduction 0:15 - Dr. Sanjeev introduces the topic of Vitamin K27 1:00 - Explaining the different types of vitamin K 2:05 - The health benefits of Vitamin K2 and its role in osteoporosis 3:55 - Atherosclerosis: Understanding the impact on heart health 5:19 - The mechanism of plaque formation and the role of Vitamin K27 6:43 - How Vitamin K27 helps remove plaque from arteries 7:53 - The potential reversibility of plaque buildup 8:44 - Availability and dosage of Vitamin K27 9:23 - Conclusion Review articles on the role of Vitamin K27 on Cardiovascular Disease: https://bit.ly/3DbmFT8 Jadhav N, Ajgaonkar S, Saha P, Gurav P, Pandey A, Basudkar V, Gada Y, Panda S, Jadhav S, Mehta D, Nair S. Molecular Pathways and Roles for Vitamin K2-7 as a Health-Beneficial Nutraceutical: Challenges and Opportunities. Front Pharmacol. 2022 Jun 14;13:896920. doi: 10.3389/fphar.2022.896920. PMID: 35774605; PMCID: PMC9237441.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9237441/ #VitaminK27 #AtherosclerosisPrevention #HeartHealthMatters

In this video, Dr. Goel discusses the fascinating benefits of Lion's Mane, a functional mushroom that has gained popularity for its potential impact on brain health. ******************** Visit our website: https://peakhuman.ca/?v=3e8d115eb4b3 Shop here: https://peakhuman.ca/shop/ SUBSCRIBE TODAY: https://bit.ly/PeakHumanLabs Join Dr. Goel as he delves into the science behind Lion's Mane and explores studies related to neurogenesis, immunomodulation, and anti-tumor properties. Discover how Lion's Mane has been used for centuries in Chinese medicine and its association with various health benefits. Dr. Goel highlights key research findings, including studies on Alzheimer's and Parkinson's diseases, metabolic improvements, and more. While most of the evidence comes from animal studies, there is one human trial that showcases promising results. Get ready to expand your knowledge about Lion's Mane and stay tuned for the next episode, where Dr. Goel will explore the hype surrounding Cordyceps. Don't forget to check the show notes for links to the studies mentioned. ****************** TIMESTAMP 0:00 - Introduction 0:15 - Dr. Goel introduces the topic of Lion's Mane 1:02 - Overview of Lion's Mane and its historical use 1:43 - Focus on brain health and its association with Lion's Mane 2:54 - Other potential benefits of Lion's Mane 3:08 - Specific use in neurodegenerative diseases 3:44 - Study 1: Reduction of cerebral amyloid beta plaque in mice 4:26 - Study 2: Improved function in mice with Alzheimer's 4:47 - Study 3: Neuroprotective properties in rats 5:27 - Study 4: Human trial showing improvement in cognitive ability 6:12 - Mention of other studies related to immune and cancer function 6:47 - Summary of neuroprotective and neurogenesis effects 7:04 - Mention of immuno-modulatory and anti-tumor effects 7:57 - Conclusion Studies - https://pubmed.ncbi.nlm.nih.gov/27350344/ - Tsai-Teng T, Chin-Chu C, Li-Ya L, Wan-Ping C, Chung-Kuang L, Chien-Chang S, Chi-Ying HF, Chien-Chih C, Shiao YJ. Erinacine A-enriched Hericium erinaceus mycelium ameliorates Alzheimer's disease-related pathologies in APPswe/PS1dE9 transgenic mice. J Biomed Sci. 2016 Jun 27;23(1):49. doi: 10.1186/s12929-016-0266-z. PMID: 27350344; PMCID: PMC4924315. erinocenes have anti dementia effects - Study by Tsai-teng et al. investigating therapeutic potential and anti dementia activity of Hericium erinaceus in mice. The mycelia and ethanol extracts reduced the cerebral amyloid beta non compact plaques and increased the amounts of the insulin degrading enzyme as well as other benefits (decreasing amount of astrocytes and plaque activated microglia, promotion of hippocampal neurogenesis). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133811/ -Zhang J, An S, Hu W, Teng M, Wang X, Qu Y, Liu Y, Yuan Y, Wang D. The Neuroprotective Properties of Hericium erinaceus in Glutamate-Damaged Differentiated PC12 Cells and an Alzheimer's Disease Mouse Model. Int J Mol Sci. 2016 Nov 1;17(11):1810. doi: 10.3390/ijms17111810. PMID: 27809277; PMCID: PMC5133811. neuroprotective properties of lions mane - Study by Zhang et al. in 2016, investigating neuroprotective effects of H. erinaceus in Alzheimers mouse model. It enhanced autonomic movements https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895996/ - Cheng JH, Tsai CL, Lien YY, Lee MS, Sheu SC. High molecular weight of polysaccharides from Hericium erinaceus against amyloid beta-induced neurotoxicity. BMC Complement Altern Med. 2016 Jun 7;16:170. doi: 10.1186/s12906-016-1154-5. PMID: 27266872; PMCID: PMC4895996. lions mane and amyloid beta plaques in rats - Study by Cheng et al. in 2016 found that H. erinaceus had neuroprotective properties against amyloid beta neurotoxicity. Free radical scavenging rate increased with a higher concentration of HE polysaccharides (antioxidant effects). Also reduced AB induced mitochondrial membrane potentials and prevented AB induced cell shrinkage and nuclear degradation https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283924/ - Li IC, Chang HH, Lin CH, Chen WP, Lu TH, Lee LY, Chen YW, Chen YP, Chen CC, Lin DP. Prevention of Early Alzheimer's Disease by Erinacine A-EnrichedHericium erinaceusMycelia Pilot Double-Blind Placebo-Controlled Study. Front Aging Neurosci. 2020 Jun 3;12:155. doi: 10.3389/fnagi.2020.00155. PMID: 32581767; PMCID: PMC7283924. study with Alzheimer’s - A double blind, placebo controlled study with human participants by Li et al. in 2020 found that an intervention of 350 mg for 49 weeks improved contrast sensitivity and increased scores on the CASI (cognitive abilities screening instrument), MMSE (mini mental state examination), and IADL (instrumental activities of daily learning) in pts with mild Alzheimers disease. #LionsManeBenefits #BrainHealthMatters #NaturalCognitiveBoost

In this video, we provide an update on the latest advancements in Alzheimer's treatment and prevention. ******************** Visit our website: https://peakhuman.ca/?v=3e8d115eb4b3 Shop here: https://peakhuman.ca/shop/ SUBSCRIBE TODAY: https://bit.ly/PeakHumanLabs We discuss the recent breakthrough medication, Leqembi, and its approval for submission to Health Canada. Additionally, we explore Eli Lilly's promising phase three trial results, which show potential in reversing or slowing down Alzheimer's progression. We delve into the concept of neurogenesis and a groundbreaking study that stimulates the growth of new brain cells to combat Alzheimer's. Furthermore, we examine the correlation between the Mediterranean diet and a lower risk of developing Alzheimer's, as revealed by a study involving over 60,000 participants. Join us as we share exciting discoveries and insights in the battle against Alzheimer's. Don't forget to subscribe, like, and share if you find this information valuable. Feel free to leave your questions in the comments, and we'll be glad to address them in future episodes. Together, let's work towards preventing and ending Alzheimer's. ****************** TIMESTAMP 0:00 - Introduction 0:15 - Discussion on Alzheimer's Treatment and Prevention 0:33 - New Alzheimer's Medication Discussed 1:00 - Explanation of Medication Nomenclature 1:33 - Reversing Alzheimer's: Clarification and Explanation 2:02 - Description of Medication's Mode of Action 2:33 - Future Prospects for Alzheimer's Treatment 2:49 - New Study on Neurogenesis 3:15 - Explanation of Neurogenesis and Its Importance 4:03 - Continued Discussion on Neurogenesis and Brain Cell Growth 5:20 - Study Relating Neurogenesis to Alzheimer's 5:50 - Light Therapy and Its Role in Stimulating Neurogenesis 6:34 - Impact of Diet on Alzheimer's 7:02 - Study on the Impact of Mediterranean Diet on Alzheimer's Risk 7:54 - Explanation of Mediterranean Diet 9:56 - Closing Discussion on the Correlation Between Mediterranean Diet and Alzheimer's Risk Study on Mediterranean Diet and Alzheimers https://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-023-02772-3 Stimulation of AD Mice with Light Therapy https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(23)00083-8 #AlzheimersPrevention #AlzheimersTreatment #BrainHealth

The early signs and symptoms of Alzheimer's are often subtle and develop slowly. It is important to be aware of these warning signs so you can identify them and seek medical advice as soon as possible. Visit our website: https://loom.ly/oRoa4OQ Shop here: https://loom.ly/5WCd_b4 SUBSCRIBE TODAY: https://bit.ly/PeakHumanLabs #alzheimers #dementia #peakhuman #alzheimersawareness #caregiver #seniorcare #dementiacare #caregiving #dementiaawareness #alzheimersdisease #elderlycare #eldercare #seniorliving #homecare #alzheimersassociation #alzheimer #healthcare #caregivers #health #caregiversupport #elderly #care #memorycare #aging #love #alzheimerscare #family #memoryloss #alzheimerscaregiver