Coley's Toxins Documentary: Dr. William Coley: The Father of Cancer Immunotherapy
Have you ever heard of Coley's toxins? Immunotherapy for cancer is all the rage right now, especially after winning a Nobel Prize in 2018.
But did you know that immunotherapy for cancer was actually discovered by bone surgeon, William B. Coley in 1891?
He noticed that some of his patients went into spontaneous remission after developing erysipelas (a bacterial infection).
Seeking to recreate the “immune” response created by the infection, Coley began injecting patients with live and dead versions of the Streptococcus bacteria.
Coley achieved responses such as durable complete remission in several types of cancer.
But if Dr. Coley was so successful, what happened to his treatment?
The truth may surprise you.
We seek to answer that question and more in this 33 minute documentary.
LINKS TO RESOURCES AND ARTICLES USED IN THIS DOCUMENTARY.
Please do your own research too.
https://www.cancer.org/content/dam/cancer-org/research/cancer-facts-and statistics/annual-cancer-facts-and-figures/2020/cancer-facts-and-figures-2020.pdf
https://www.cancer.org/research/cancer-facts-statistics/all-cancer-facts-figures/ cancer-facts-figures-2020.html
https://www.cancer.org/research/cancer-facts-statistics/all-cancer-facts-figures.html https://chipsahospital.org/coleys-toxins/
https://www.cancerresearch.org/blog/april-2015/what-ever-happened-to-coleys toxins
https://www.cancerresearch.org/about-cri/cri-history
https://www.mskcc.org/news/immunotherapy-revolutionizing-cancer treatment-1891
https://www.kreftfri.no/wp-content/uploads/2019/10/Bioimmunoadjuvants-for-the treatment-of-neoplastic-and-infectious-disease-Coleys-legacy revisited.-William-K.-Decker-Amar-Safdar.pdf
https://pmj.bmj.com/content/79/938/672
https://jamanetwork.com/journals/jama/article-abstract/450755
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1888599/
https://pubmed.ncbi.nlm.nih.gov/29719818/
https://www.mskcc.org/news/immunotherapy-revolutionizing-cancer treatment-1891
http://gerson-research.org/coleys-toxins/
https://conquer-magazine.com/issues/special-issues/cancer-immunotherapy june-2017/23-cancer-immunotherapy-drugs-approved-by-the-fda-since-2015
https://www.pfizer.com/news/press-release/press-release-detail/ pfizer_to_acquire_coley_pharmaceutical_group
https://www.cancer.org/treatment/treatments-and-side-effects/treatment-types/ immunotherapy/what-is-immunotherapy.html
https://www.tandfonline.com/doi/full/10.3109/0284186X.2012.711954 https://www.ncbi.nlm.nih.gov/books/NBK279364/
https://www.discovermagazine.com/health/germ-of-an-idea-william-coleys-cancer killing-toxins
https://www.cancer.gov/publications/dictionaries/cancer-terms/def/immune checkpoint-inhibitor
https://www.mskcc.org/about/history-milestones
https://www.hindawi.com/journals/sarcoma/2011/457532/
https://www.cancer.org/cancer/cancer-basics/history-of-cancer/cancer-treatment radiation.html
https://www.cancer.net/navigating-cancer-care/how-cancer-treated/immunotherapy and-vaccines/understanding-immunotherapy
https://slate.com/human-interest/2013/02/where-do-the-millions-of-cancer research-dollars-go-every-year.html
https://www.asbestos.com/featured-stories/high-cost-of-cancer-treatment/
https://www.usnews.com/news/blogs/data-mine/2015/05/05/global-cancer spending-reaches-100b
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