My NMN Experiment

In this video we will look at NAC as a supplement, what benefits taking it could yield and also the possible side-effects and the daily dosages. Renue by Science 10% Discount Code: MYNMN (https://renuebyscience.com/?rfsn=5692699.331801&coupon-code=MYNMN) DoNotAge 10% Discount Code: MYNMN (https://bit.ly/2VBDgNt) Renue by Science 15% Subscription Service Discount Code: MYNMNSUB I hope you enjoy my content and find it interesting or informative, if so, please consider supporting the channel by using one of the links below: * Buy me a Kofi: https://ko-fi.com/mynmnexperiment * Patreon: https://bit.ly/3hhfjl5 * SubscribeStar: https://bit.ly/3psYo23 My Current Anti-Aging Protocol: • 1.5 grams of NMN (https://bit.ly/3c2Fxt8) • 1.5 grams of Trans-resveratrol (Tue, Thu & Sat) (https://bit.ly/3yxeqy2) • 500mg Metformin • 1.5 grams of TMG (https://bit.ly/3oe1Ted) • 5,000 IU (International Units) of vitamin D3 (https://bit.ly/3P32hYH) • 120 mcg (micrograms) of vitamin K2 (Mk 7) (https://bit.ly/3PhkBgn) • 250mg Magnesium (L-Threonate) (https://bit.ly/3O4pZ5o) • 200mg high molecular weight hyaluronic acid (https://bit.ly/3P0Z4c2) • 2,400mg of Fisetin, on the 1st, 2nd & 3rd of each month (https://bit.ly/3P2rSB0) • 2,400mg of Quercetin, on the 1st, 2nd & 3rd of each month (https://bit.ly/3IzulAy) • 81mg of aspirin (https://bit.ly/3uFjtem) • 800mg SIRT6 Activator • 600mg DIM Links: https://pubmed.ncbi.nlm.nih.gov/24080471/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3036554/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241507/ https://pubmed.ncbi.nlm.nih.gov/10968500/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343415/ https://pubmed.ncbi.nlm.nih.gov/19722195/ https://pubmed.ncbi.nlm.nih.gov/19280424/ https://bit.ly/3SbLF3h https://bit.ly/3IcsMsl https://www.lifeextension.com/magazine/2010/5/n-acetyl-cysteine http://clevelandclinic.org/reproductiveresearchcenter/docs/agradoc162A.pdf https://www.mskcc.org/cancer-care/integrative-medicine/herbs/n-acetylcysteine https://www.fda.gov/food/cfsan-constituent-updates/fda-releases-final-guidance-enforcement-discretion-certain-nac-products Research suggests that N-acetyl cysteine (NAC) - the supplement form of the semi-essential amino acid L-cysteine - is an effective, safe and low-cost treatment option for a range of conditions, including those that are both acute and chronic. Not only has been it been used for three decades as an effective mucolytic agent (mucous-thinner), but it also has uses including reducing inflammation, protecting the liver, and preventing/treating drug toxicity, insulin resistance and infertility due to PCOS to name a few. N-acetyl cysteine (NAC), the supplement form of cysteine, is an amino acid that helps the body create and use protective antioxidants. While cysteine is found in many high-protein foods, NAC is only acquired by taking supplements or prescription drugs. Because the human body can create some NAC from some other amino acids, so it is considered to be a “semi-essential amino acid.” That means there isn’t a daily requirement of NAC that you must get from your diet, but getting higher amounts can benefit some people. NAC is involved in the regulation of the glutamatergic system. In other words, as a precursor of L-cysteine, which results in glutathione biosynthesis, NAC (along with glutamine and glycine) is an amino acid that is needed to produce what’s arguably the most important antioxidant in the human body. The most important NAC mechanisms of action are its antioxidant and its anti-inflammatory effects. These are due to its ability to increase glutathione levels, scavenge free radicals and reduce oxidative stress. This is why it’s recommended as a potential treatment for different disorders resulting from free oxygen radicals, such as liver disease, Alzheimer’s, Parkinson’s and some cancers. Studies have shown no maternal or fetal harmful effects of NAC treatment. Certain studies have even found that NAC used in combination with vitamin E, or vitamins A and E, and essential fatty acids can reduce reactive oxygen species (ROS) and lead to pregnancy rate improvements in those struggling to become and stay pregnant, especially women with PCOS. This is because it increases levels of the antioxidant glutathione, which positively acts on insulin secretion and reduces insulin resistance, which is believed to be associated with PCOS. DISCLAIMER: This video and description contain discount codes, which means that if you use the code, I will receive a small commission. FAIR-USE COPYRIGHT DISCLAIMER Copyright Disclaimer Under Section 107 of the Copyright Act 1976, allowance is made for "fair use" for purposes such as criticism, commenting, news reporting, teaching, scholarship, and research. Fair use is a use permitted by copyright statute that might otherwise be infringing. Non-profit, educational, or personal use tips the balance in favor of fair use. #NAC #Glutathione #GlyNAC

This week’s MEGA giveaway from DoNotAge is 366 x 500mg of Apigenin, which would normally sell for a whopping $260. DoNotAge 10% Discount Code: MYNMN (https://bit.ly/2VBDgNt) I hope you enjoy my content and find it interesting or informative, if so, please consider supporting the channel by using one of the links below: * Buy me a Kofi: https://ko-fi.com/mynmnexperiment * Patreon: https://bit.ly/3hhfjl5 * SubscribeStar: https://bit.ly/3psYo23 My Current Anti-Aging Protocol: • 1.5 grams of NMN (https://bit.ly/3c2Fxt8) • 1.5 grams of Trans-resveratrol (Tue, Thu & Sat) (https://bit.ly/3yxeqy2) • 500mg Metformin • 1.5 grams of TMG (https://bit.ly/3oe1Ted) • 5,000 IU (International Units) of vitamin D3 (https://bit.ly/3P32hYH) • 120 mcg (micrograms) of vitamin K2 (Mk 7) (https://bit.ly/3PhkBgn) • 250mg Magnesium (L-Threonate) (https://bit.ly/3O4pZ5o) • 200mg high molecular weight hyaluronic acid (https://bit.ly/3P0Z4c2) • 2,400mg of Fisetin, on the 1st, 2nd & 3rd of each month (https://bit.ly/3P2rSB0) • 2,400mg of Quercetin, on the 1st, 2nd & 3rd of each month (https://bit.ly/3IzulAy) • 81mg of aspirin (https://bit.ly/3uFjtem) • 800mg SIRT6 Activator • 600mg DIM DISCLAIMER: The Video Content has been made available for informational and educational purposes only. The video creator does not make any representation or warranties with respect to the accuracy, applicability, fitness, or completeness of the Video Content. The Video Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. The video creator hereby disclaims any and all liability to any party for any direct, indirect, implied, punitive, special, incidental or other consequential damages arising directly or indirectly from any use of the Video Content, which is provided as is, and without warranties. Best Apigenin brand in 2023, best Apigenin supplement 2023, best Apigenin supplements reviews, best Apigenin, best Apigenin supplement, best Apigenin supplement on the market, best Apigenin 2023, Apigenin Human Trial, Dr. David Sinclair, David Sinclair PhD, DoNotAge.org, DoNotAge, Renue by Science, Renue by Science reviews, Renue by Science Apigenin, ProHealth Longevity, ProHealth Longevity reviews, ProHealth longevity Apigenin, Apigenin, Apigenin Powder, Apigenin Supplement, Apigenin Capsules, Apigenin tablets, Cheapest Apigenin Supplement, where to buy Apigenin, Apigenin side effects, Apigenin Supplement Review DISCLAIMER: This video and description contain discount codes, which means that if you use the code, I will receive a small commission. FAIR-USE COPYRIGHT DISCLAIMER Copyright Disclaimer Under Section 107 of the Copyright Act 1976, allowance is made for "fair use" for purposes such as criticism, commenting, news reporting, teaching, scholarship, and research. Fair use is a use permitted by copyright statute that might otherwise be infringing. Non-profit, educational, or personal use tips the balance in favor of fair use. #Apigenin #DoNotAge #Giveaway

A study out of New Zealand seems to show that 6 minutes of a particular type of exercise boosts a protein in the brain that works to fend of the diseases of aging. DoNotAge.org 10% Discount Code: MYNMN (https://bit.ly/2VBDgNt) Renue by Science 10% Discount Code: MYNMN (https://renuebyscience.com/?rfsn=5692699.331801&coupon-code=MYNMN) Renue by Science 15% Subscription Service Discount Code: MYNMNSUB I hope you enjoy my content and find it interesting or informative, if so, please consider supporting the channel by using one of the links below: * Buy me a Kofi: https://ko-fi.com/mynmnexperiment * Patreon: https://bit.ly/3hhfjl5 * SubscribeStar: https://bit.ly/3psYo23 My Current Anti-Aging Protocol: • 1.5 grams of NMN (https://bit.ly/3c2Fxt8) • 1.5 grams of Trans-resveratrol (Tue, Thu & Sat) (https://bit.ly/3yxeqy2) • 500mg Metformin • 1.5 grams of TMG (https://bit.ly/3oe1Ted) • 5,000 IU (International Units) of vitamin D3 (https://bit.ly/3P32hYH) • 120 mcg (micrograms) of vitamin K2 (Mk 7) (https://bit.ly/3PhkBgn) • 250mg Magnesium (L-Threonate) (https://bit.ly/3O4pZ5o) • 200mg high molecular weight hyaluronic acid (https://bit.ly/3P0Z4c2) • 2,400mg of Fisetin, on the 1st, 2nd & 3rd of each month (https://bit.ly/3P2rSB0) • 2,400mg of Quercetin, on the 1st, 2nd & 3rd of each month (https://bit.ly/3IzulAy) • 81mg of aspirin (https://bit.ly/3uFjtem) • 800mg SIRT6 Activator • 600mg DIM Links: https://pubmed.ncbi.nlm.nih.gov/36631068/#:~:text=Fasting%20for%2020%20h%20caused,in%20peripheral%20circulation%20at%20rest. https://physoc.onlinelibrary.wiley.com/doi/10.1113/JP283582 https://www.medicalnewstoday.com/articles/6-minutes-of-hiit-may-help-delay-onset-of-alzheimers-parkinsons https://www.upi.com/Health_News/2023/01/12/new-zealand-study-high-intensity-exercise-brain-health/4641673500756/ https://www.sciencedaily.com/releases/2023/01/230112090919.htm Six minutes of high-intensity exercise could extend the lifespan of a healthy brain and delay the onset of neurodegenerative disorders, such as Alzheimer's disease and Parkinson's disease. This new research published in The Journal of Physiology showed that a short but intense bout of cycling increases the production of a specialized protein that is essential for brain formation, learning and memory, and could protect the brain from age-related cognitive decline. This insight on exercise is part of the drive to develop accessible, equitable and affordable non-pharmacological approaches that anyone can adopt to promote healthy aging. The specialized protein named brain-derived neurotrophic factor (BDNF) promotes neuroplasticity and the survival of neurons. Neuroplasticity is the mechanism by which the brain forms new connections and pathways. Animal studies have shown that increasing the availability of BDNF encourages the formation and storage of memories, enhances learning and overall boosts cognitive performance. These key roles and its apparent neuro-protective qualities have led to more interest into BDNF for aging research. Travis Gibbons, a PhD candidate at the University of Otago and Lead Author of the study said "BDNF has shown great promise in animal models, but pharmaceutical interventions have thus far failed to safely harness the protective power of BDNF in humans. We saw the need to explore non-pharmacological approaches that can preserve the brain's capacity which humans can use to naturally increase BDNF to help with healthy aging." To tease apart the influence of fasting and exercise on BDNF production, the researchers, from the University of Otago, New Zealand, compared the following factors to study the isolated and interactive effects: • First was fasting for 20 hours • Second, light exercise (90-minutes of low intensity cycling) • Third, was high-intensity exercise (six-minute bouts of vigorous cycling) • And fourth was a combination of fasting and exercise   They found that brief but vigorous exercise was the most efficient way to increase BDNF compared to one day of fasting, and that was with or without a lengthy session of light exercise. High intensity exercise increased BDNF by four to five-fold (396 pg L-1 to 1170 pg L-1); an increase of 774 points Fasting showed no change in BDNF concentration Low intensity, prolonged activity showed a slight increase in BDNF concentration, (336 pg L-1 to 390 pg L-1); and increase of only 54 points. DISCLAIMER: This video and description contain discount codes, which means that if you use the code, I will receive a small commission. FAIR-USE COPYRIGHT DISCLAIMER Copyright Disclaimer Under Section 107 of the Copyright Act 1976, allowance is made for "fair use" for purposes such as criticism, commenting, news reporting, teaching, scholarship, and research. Fair use is a use permitted by copyright statute that might otherwise be infringing. Non-profit, educational, or personal use tips the balance in favor of fair use. #HIIT #Dementia #fitnessmotivation

It appears from this latest study that steadily increasing weight up to, but not beyond overweight produces the best mortality outcome. Renue by Science 10% Discount Code: MYNMN (https://renuebyscience.com/?rfsn=5692699.331801&coupon-code=MYNMN) Renue by Science 15% Subscription Service Discount Code: MYNMNSUB DoNotAge.org 10% Discount Code: MYNMN (https://bit.ly/2VBDgNt) I hope you enjoy my content and find it interesting or informative, if so, please consider supporting the channel by using one of the links below: * Buy me a Kofi: https://ko-fi.com/mynmnexperiment * Patreon: https://bit.ly/3hhfjl5 * SubscribeStar: https://bit.ly/3psYo23 My Current Anti-Aging Protocol: • 1.5 grams of NMN (https://bit.ly/3c2Fxt8) • 1.5 grams of Trans-resveratrol (Tue, Thu & Sat) (https://bit.ly/3yxeqy2) • 500mg Metformin • 1.5 grams of TMG (https://bit.ly/3oe1Ted) • 5,000 IU (International Units) of vitamin D3 (https://bit.ly/3P32hYH) • 120 mcg (micrograms) of vitamin K2 (Mk 7) (https://bit.ly/3PhkBgn) • 250mg Magnesium (L-Threonate) (https://bit.ly/3O4pZ5o) • 200mg high molecular weight hyaluronic acid (https://bit.ly/3P0Z4c2) • 2,400mg of Fisetin, on the 1st, 2nd & 3rd of each month (https://bit.ly/3P2rSB0) • 2,400mg of Quercetin, on the 1st, 2nd & 3rd of each month (https://bit.ly/3IzulAy) • 81mg of aspirin (https://bit.ly/3uFjtem) • 800mg SIRT6 Activator • 600mg DIM Links: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009819/ https://pubmed.ncbi.nlm.nih.gov/33493649/ https://stacks.cdc.gov/view/cdc/111314 https://bit.ly/3JVCVw2 https://bit.ly/3DODYtV https://www.sciencedirect.com/science/article/abs/pii/S1047279721000090?via%3Dihub This study suggests that people who start adulthood with a BMI (Body Mass Index) that is in the normal range, and then move onto being overweight in later life - but never reaching obese status - tended to live the longest. Adults in this category even lived longer than even those whose BMI stayed in the normal range throughout their life. Those who started adulthood as obese and continued to add weight as they aged had the highest mortality rate. Hui Zheng PhD, lead author of the study and associate professor of sociology at Ohio State University said: "The impact of weight gain on mortality is complex. It depends on both the timing and the magnitude of weight gain and where BMI started. The main message is that for those who start at a normal weight in early adulthood, gaining a modest amount of weight throughout life and entering the overweight category in later adulthood can actually increase the probability of survival."  Similar results were found in two generations of Framingham Heart Study participants, this study has followed the medical histories of residents of one city in Massachusetts and their children for decades. But the study has shown worrying trends for the younger generation, they are becoming overweight and obese sooner in their lives than their parents, and as a result are more likely to have deaths linked to cumulative obesity. For this study the researchers used data on 4,576 people from the original cohort of the Framingham Heart Study, and for 3,753 of their children. The Framingham Heart Study started in 1948 and followed the original participants through until 2010. Their children of the original participants, the second generation, were followed from 1971 to 2014. For both generations, the researchers looked at data from those aged from 31 to 80. The main measure was BMI, which is based on a person's height and weight and is used as a rule of thumb to categorize a person as underweight, normal weight, overweight or obese. In both generations, those who started at a normal weight and moved slowly onto being overweight later in life, but never actually became obese, were the most likely to survive the longest. • Those who stayed at normal weight throughout their life were the next most likely to survive longer. • Followed by those who were overweight, but stayed stable. • Next came those who were at the lower level of normal weight. • In the older generation, those who were overweight and lost weight came next. • The least likely to survive were the two trajectories that included those who started off as obese, and then continued to gain weight throughout their lives. DISCLAIMER: This video and description contain discount codes, which means that if you use the code, I will receive a small commission. FAIR-USE COPYRIGHT DISCLAIMER Copyright Disclaimer Under Section 107 of the Copyright Act 1976, allowance is made for "fair use" for purposes such as criticism, commenting, news reporting, teaching, scholarship, and research. Fair use is a use permitted by copyright statute that might otherwise be infringing. Non-profit, educational, or personal use tips the balance in favor of fair use. #BodyMassIndex #BMI #BMIChart

When it comes to reducing visceral fat, this study shows that one class of food is more beneficial than others, let’s see what it is. DoNotAge.org 10% Discount Code: MYNMN (https://bit.ly/2VBDgNt) Renue by Science 10% Discount Code: MYNMN (https://renuebyscience.com/?rfsn=5692699.331801&coupon-code=MYNMN) Renue by Science 15% Subscription Service Discount Code: MYNMNSUB I hope you enjoy my content and find it interesting or informative, if so, please consider supporting the channel by using one of the links below: * Buy me a Kofi: https://ko-fi.com/mynmnexperiment * Patreon: https://bit.ly/3hhfjl5 * SubscribeStar: https://bit.ly/3psYo23 My Current Anti-Aging Protocol: • 1.5 grams of NMN (https://bit.ly/3c2Fxt8) • 1.5 grams of Trans-resveratrol (Tue, Thu & Sat) (https://bit.ly/3yxeqy2) • 500mg Metformin • 1.5 grams of TMG (https://bit.ly/3oe1Ted) • 5,000 IU (International Units) of vitamin D3 (https://bit.ly/3P32hYH) • 120 mcg (micrograms) of vitamin K2 (Mk 7) (https://bit.ly/3PhkBgn) • 250mg Magnesium (L-Threonate) (https://bit.ly/3O4pZ5o) • 200mg high molecular weight hyaluronic acid (https://bit.ly/3P0Z4c2) • 2,400mg of Fisetin, on the 1st, 2nd & 3rd of each month (https://bit.ly/3P2rSB0) • 2,400mg of Quercetin, on the 1st, 2nd & 3rd of each month (https://bit.ly/3IzulAy) • 81mg of aspirin (https://bit.ly/3uFjtem) • 800mg SIRT6 Activator • 600mg DIM Links: https://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-022-02525-8 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9523931/ https://pubmed.ncbi.nlm.nih.gov/36175997/ https://cris.bgu.ac.il/en/datasets/the-effect-of-high-polyphenol-mediterranean-diet-on-visceral-adip https://pubmed.ncbi.nlm.nih.gov/27552476/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160559/ https://pubmed.ncbi.nlm.nih.gov/32559477/ This study pitched two variants of the Mediterranean diet against each other in a randomized controlled trial (more on exactly a controlled trial is later); scientists found that the one which contained more polyphenols was more effective for weight loss. IMHO, this gives the impression that there may only be a few variants of the Mediterranean diet, the Mediterranean Sea - from the Strait of Gibraltar to the shores of Southwestern Turkey is approximately 2,500 miles (4,000 km), if superimposed on the USA, it would stretch from Washington DC to Los Angeles - there is no way that all cuisines could be represented in a 2 diet study, IMHO. That said, let’s see what they say. A healthy diet is one of the most powerful anti-aging interventions available today, but the question of which diet is the healthiest is very much open to debate, due to the sheer number of factors involved. The Mediterranean diet, rich in olive oil, vegetables, legumes, fish, and nuts, and the author says that it is probably the most evidence-based of all; my point here is where does the evidence come from, trusted sources? Numerous epidemiological studies, and a handful of interventional studies, have linked the Mediterranean diet to various positive health outcomes, including decreased overall mortality along with a lower incidence of cardiovascular diseases and cancer. Epidemiological studies sound impressive, but are they reliable? Many people wanting to make their point will direct you towards study results, but what kind of study, a reliable one? There are many issues with epidemiologic studies, one being a high dropout rate. Another is reporting bias or recall bias; this occurs when the study group and the control group systematically report differently even though they exposed was the same stimuli. There can also be problems with accuracy of diagnosis and/or causes of death etc. years after the fact. Also not including all confounding factors, things that can skew the results such as age, exercise regime, smoking history, medications taken etc. In this study scientists wanted to dig deeper and understand which of the many ingredients of the Mediterranean diet make it healthy. In this new paper, the researchers used an interesting study design to elucidate the role of polyphenols, a class of phytochemicals known for their antioxidant and anti-inflammatory properties. Polyphenols are abundant in berries, nuts, vegetables, tea, coffee, and dietary supplements. DISCLAIMER: This video and description contain discount codes, which means that if you use the code, I will receive a small commission. FAIR-USE COPYRIGHT DISCLAIMER Copyright Disclaimer Under Section 107 of the Copyright Act 1976, allowance is made for "fair use" for purposes such as criticism, commenting, news reporting, teaching, scholarship, and research. Fair use is a use permitted by copyright statute that might otherwise be infringing. Non-profit, educational, or personal use tips the balance in favor of fair use. #LongevityDiet #antiagingdiet #Healthylifestyle

This latest research has shown that NMN actually blunted the spread of an existing cancer. Renue by Science 10% Discount Code: MYNMN (https://renuebyscience.com/?rfsn=5692699.331801&coupon-code=MYNMN) Renue by Science 15% Subscription Service Discount Code: MYNMNSUB DoNotAge.org 10% Discount Code: MYNMN (https://bit.ly/2VBDgNt) I hope you enjoy my content and find it interesting or informative, if so, please consider supporting the channel by using one of the links below: * Buy me a Kofi: https://ko-fi.com/mynmnexperiment * Patreon: https://bit.ly/3hhfjl5 * SubscribeStar: https://bit.ly/3psYo23 My Current Anti-Aging Protocol: • 1.5 grams of NMN (https://bit.ly/3c2Fxt8) • 1.5 grams of Trans-resveratrol (Tue, Thu & Sat) (https://bit.ly/3yxeqy2) • 500mg Metformin • 1.5 grams of TMG (https://bit.ly/3oe1Ted) • 5,000 IU (International Units) of vitamin D3 (https://bit.ly/3P32hYH) • 120 mcg (micrograms) of vitamin K2 (Mk 7) (https://bit.ly/3PhkBgn) • 250mg Magnesium (L-Threonate) (https://bit.ly/3O4pZ5o) • 200mg high molecular weight hyaluronic acid (https://bit.ly/3P0Z4c2) • 2,400mg of Fisetin, on the 1st, 2nd & 3rd of each month (https://bit.ly/3P2rSB0) • 2,400mg of Quercetin, on the 1st, 2nd & 3rd of each month (https://bit.ly/3IzulAy) • 81mg of aspirin (https://bit.ly/3uFjtem) • 800mg SIRT6 Activator • 600mg DIM Links: https://www.nature.com/articles/s41388-023-02592-y https://pubmed.ncbi.nlm.nih.gov/36690678/ https://www.researchgate.net/publication/367342166_NAD_supplementation_limits_triple-negative_breast_cancer_metastasis_via_SIRT1-P66Shc_signaling https://www.lifespan.io/news/nad-helps-natural-killer-cells-to-fight-cancer/ Jiang, Y., Luo, Z., Gong, Y. et al. NAD+ supplementation limits triple-negative breast cancer metastasis via SIRT1-P66Shc signaling. Oncogene (2023). Yaku, K., Okabe, K., Hikosaka, K., & Nakagawa, T. (2018). NAD metabolism in cancer therapeutics. Frontiers in oncology, 8, 622. Cantó, C., Menzies, K. J., & Auwerx, J. (2015). NAD+ metabolism and the control of energy homeostasis: a balancing act between mitochondria and the nucleus. Cell metabolism, 22(1), 31-53. Kerksick, C., & Willoughby, D. (2005). The antioxidant role of glutathione and N-acetyl-cysteine supplements and exercise-induced oxidative stress. Journal of the international society of sports nutrition, 2(2), 38. Porporato, P. E., Payen, V. L., Pérez-Escuredo, J., De Saedeleer, C. J., Danhier, P., Copetti, T., … & Sonveaux, P. (2014). A mitochondrial switch promotes tumor metastasis. Cell reports, 8(3), 754-766. Like many bio-molecules, NAD+ is a double-edged sword, especially when looking into its self-contradictory relationship with cancer. Note there that I said it was NAD that was the doubled edged sword, and not NMN. On the one hand, NAD+ is used as fuel by many types of cancer cells. And on the other hand, it can boosts an anti-cancer immune response. Other NAD-dependent enzymes such as the Sirtuins and PARP also seem to have a context-dependent effect on cancer. In this study researchers studied the effects of NAD+ on Triple-Negative Breast Cancer (TNBC). TNBC cells lack the three common receptors that are usually found on the surfaces of breast cancer cells, which limit the full array of therapeutic options that are usually open to doctors. The researchers initially generated primary tumors by injecting HCC1937 cancer cells, a common model of TNBC, into the mammary fat pads of immune-compromised mice. Continuous treatment with NMN significantly impeded tumor growth and cancer metastasis. Similar results were obtained using actual TNBC cells taken from a cancer patient. The researchers then proceeded to study NAD+ metabolism in vitro (meaning in glass, so outside of their normal biological context) and found that NMN supplementation rapidly increased intracellular NAD+ levels; as it usually does. While the treatment did not affect the proliferation of cancer cells, it slowed their migration and invasion. RNA sequencing of tumor samples revealed that NMN supplementation led to the activation of genes involved in longevity-regulating pathways and glutathione metabolism. It has been argued that Glutathione is probably the most important antioxidant that humans produce. Recent studies have shown that some protective effects of NAD+ might be attributed to its regulation of SIRT1, a member of the sirtuin family. DISCLAIMER: This video and description contain discount codes, which means that if you use the code, I will receive a small commission. FAIR-USE COPYRIGHT DISCLAIMER Copyright Disclaimer Under Section 107 of the Copyright Act 1976, allowance is made for "fair use" for purposes such as criticism, commenting, news reporting, teaching, scholarship, and research. Fair use is a use permitted by copyright statute that might otherwise be infringing. Non-profit, educational, or personal use tips the balance in favor of fair use. #DavidSinclair #RenueByScience #DoNotAge

This week’s giveaway is two jars of their 100 grams of NMN, so 200 grams of NMN, as always this is 3rd party tested for purity and heavy meats and is produced in an FDA approved facility. Two containers would normally sell for $209.90. Renue by Science 10% Discount Code: MYNMN (https://renuebyscience.com/?rfsn=5692699.331801&coupon-code=MYNMN) Renue by Science 15% Subscription Service Discount Code: MYNMNSUB I hope you enjoy my content and find it interesting or informative, if so, please consider supporting the channel by using one of the links below: * Buy me a Kofi: https://ko-fi.com/mynmnexperiment * Patreon: https://bit.ly/3hhfjl5 * SubscribeStar: https://bit.ly/3psYo23 My Current Anti-Aging Protocol: • 1.5 grams of NMN (https://bit.ly/3c2Fxt8) • 1.5 grams of Trans-resveratrol (Tue, Thu & Sat) (https://bit.ly/3yxeqy2) • 500mg Metformin • 1.5 grams of TMG (https://bit.ly/3oe1Ted) • 5,000 IU (International Units) of vitamin D3 (https://bit.ly/3P32hYH) • 120 mcg (micrograms) of vitamin K2 (Mk 7) (https://bit.ly/3PhkBgn) • 250mg Magnesium (L-Threonate) (https://bit.ly/3O4pZ5o) • 200mg high molecular weight hyaluronic acid (https://bit.ly/3P0Z4c2) • 2,400mg of Fisetin, on the 1st, 2nd & 3rd of each month (https://bit.ly/3P2rSB0) • 2,400mg of Quercetin, on the 1st, 2nd & 3rd of each month (https://bit.ly/3IzulAy) • 81mg of aspirin (https://bit.ly/3uFjtem) • 800mg SIRT6 Activator • 600mg DIM DISCLAIMER: The Video Content has been made available for informational and educational purposes only. The video creator does not make any representation or warranties with respect to the accuracy, applicability, fitness, or completeness of the Video Content. The Video Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. The video creator hereby disclaims any and all liability to any party for any direct, indirect, implied, punitive, special, incidental or other consequential damages arising directly or indirectly from any use of the Video Content, which is provided as is, and without warranties. Best NMN brand in 2023, best NMN supplement 2023, best NMN supplements reviews, best NMN, best NMN supplement, best NMN supplement on the market, best NMN 2023,NMN Human Trial, Dr. David Sinclair, David Sinclair PhD, David Sinclair Harvard, DoNotAge.org, DoNotAge, Renue by Science, Renue by Science reviews, Renue by Science NMN, ProHealth Longevity, ProHealth longevity NMN,NMN, NMN Supplement, Cheapest NMN Supplement, where to buy NMN,NMN side effects, NMN Supplement Review DISCLAIMER: This video and description contain discount codes, which means that if you use the code, I will receive a small commission. FAIR-USE COPYRIGHT DISCLAIMER Copyright Disclaimer Under Section 107 of the Copyright Act 1976, allowance is made for "fair use" for purposes such as criticism, commenting, news reporting, teaching, scholarship, and research. Fair use is a use permitted by copyright statute that might otherwise be infringing. Non-profit, educational, or personal use tips the balance in favor of fair use. #RenueByScience #NMN #Giveaway

This supplement was approved by the FDA in 2018, it has the ability to restore the mitochondria; Mitochondrial dysfunction being one of the nine ‘hallmarks of aging.’ DoNotAge.org 10% Discount Code: MYNMN (https://bit.ly/2VBDgNt) Renue by Science 10% Discount Code: MYNMN (https://renuebyscience.com/?rfsn=5692699.331801&coupon-code=MYNMN) Renue by Science 15% Subscription Service Discount Code: MYNMNSUB I hope you enjoy my content and find it interesting or informative, if so, please consider supporting the channel by using one of the links below: * Buy me a Kofi: https://ko-fi.com/mynmnexperiment * Patreon: https://bit.ly/3hhfjl5 * SubscribeStar: https://bit.ly/3psYo23 My Current Anti-Aging Protocol: • 1.5 grams of NMN (https://bit.ly/3c2Fxt8) • 1.5 grams of Trans-resveratrol (Tue, Thu & Sat) (https://bit.ly/3yxeqy2) • 500mg Metformin • 1.5 grams of TMG (https://bit.ly/3oe1Ted) • 5,000 IU (International Units) of vitamin D3 (https://bit.ly/3P32hYH) • 120 mcg (micrograms) of vitamin K2 (Mk 7) (https://bit.ly/3PhkBgn) • 250mg Magnesium (L-Threonate) (https://bit.ly/3O4pZ5o) • 200mg high molecular weight hyaluronic acid (https://bit.ly/3P0Z4c2) • 2,400mg of Fisetin, on the 1st, 2nd & 3rd of each month (https://bit.ly/3P2rSB0) • 2,400mg of Quercetin, on the 1st, 2nd & 3rd of each month (https://bit.ly/3IzulAy) • 81mg of aspirin (https://bit.ly/3uFjtem) • 800mg SIRT6 Activator • 600mg DIM Links: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133463/ https://pubmed.ncbi.nlm.nih.gov/35050355/ https://pubmed.ncbi.nlm.nih.gov/35584623/ https://pubmed.ncbi.nlm.nih.gov/35778837/ https://pubmed.ncbi.nlm.nih.gov/28757461/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417212/ https://www.clinicaltrials.gov/ct2/show/NCT04783207 https://clinicaltrials.gov/ct2/show/NCT03464500 https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2788244 http://pdf.amazentis.com/pdf/Amazentis_Timeline_Launch_PR_7.27.2020_v9_Final.pdf Mukku, Murray, Espin, & Perdew (2018), “Urolithin A Is a Dietary Microbiota-Derived Human Aryl Hydrocarbon Receptor Antagonist”, NCBI Singh, Andreux, Blanko, Auwerx, & Rinsch (2019), “Urolithin A, a Gut Microbiome Derived Metabolite”, Academic D’Amico, Andreux, Valdes, Singh, Rinsch, & Awerex (2021), “Impact of the Natural Compound Urolithin A on Health, Disease, and Aging”, Science Direct Aebischer, Blanco-bose, Kern, Dunngalvin, Andreux, D’Amico, Singh, & Rinsch (2021), “Direct supplementation with Urolithin A overcomes limitations of dietary exposure and gut microbiome variability”, Nature What is Urolithin A, how do we produce it, and can everybody produce it naturally? Urolithin A is a naturally derived nutrient which is processed by microflora in our gut microbiome (microflora are bacteria and microscopic algae). Urolithin A is a postbiotic (I’m sure you have heard of prebiotics and probiotics) - Urolithin A is synthesized after eating certain foods high in polyphenols like berries, nuts and pomegranates. Postbiotics are by-products from the gut that can act as health-promoting compounds. Taking a supplement for this nutrient may necessary as not everyone nowadays is capable of producing it naturally. Research has revealed that only 12% of people are proficient in producing Urolithin A naturally in the body. Unfortunately, our mitochondrial function declines with age, impairing the mitochondria’s ability to produce enough energy for our bodies to function as they did in our youth. Mitochondrial dysfunction is one of the nine ‘hallmarks of aging’ that cause cellular and molecular damage to the body that can lead to age-related illness. Known as an antagonistic hallmark, mitochondrial dysfunction can cause loss of muscle strength, which many people experience from their 40’s onwards. This can lead to a serious condition known as sarcopenia that affects 30% of older people and is associated with poor mobility, frailty and fall-related injuries. For those who are less physically able, Urolithin A can be used to boost mitochondrial health without the need for exercise. Available from the diet and more effectively, from dietary supplements, Urolithin A has been shown to promote mitochondrial health and muscle endurance. It does this by improving mitochondrial activity, specifically by activating the process of mitophagy. DISCLAIMER: This video and description contain discount codes, which means that if you use the code, I will receive a small commission. FAIR-USE COPYRIGHT DISCLAIMER Copyright Disclaimer Under Section 107 of the Copyright Act 1976, allowance is made for "fair use" for purposes such as criticism, commenting, news reporting, teaching, scholarship, and research. Fair use is a use permitted by copyright statute that might otherwise be infringing. Non-profit, educational, or personal use tips the balance in favor of fair use. #UrolithinA #Mitochondria #HallmarksOfAging

a new study out of the Brigham and Women’s Hospital in Boston has shown that the later in the day you eat has a profound effect on the hormones that control your appetite and on your circadian rhythm. DoNotAge.org 10% Discount Code: MYNMN (https://bit.ly/2VBDgNt) Renue by Science 10% Discount Code: MYNMN (https://renuebyscience.com/?rfsn=5692699.331801&coupon-code=MYNMN) Renue by Science 15% Subscription Service Discount Code: MYNMNSUB I hope you enjoy my content and find it interesting or informative, if so, please consider supporting the channel by using one of the links below: * Buy me a Kofi: https://ko-fi.com/mynmnexperiment * Patreon: https://bit.ly/3hhfjl5 * SubscribeStar: https://bit.ly/3psYo23 My Current Anti-Aging Protocol: • 1.5 grams of NMN (https://bit.ly/3c2Fxt8) • 1.5 grams of Trans-resveratrol (Tue, Thu & Sat) (https://bit.ly/3yxeqy2) • 500mg Metformin • 1.5 grams of TMG (https://bit.ly/3oe1Ted) • 5,000 IU (International Units) of vitamin D3 (https://bit.ly/3P32hYH) • 120 mcg (micrograms) of vitamin K2 (Mk 7) (https://bit.ly/3PhkBgn) • 250mg Magnesium (L-Threonate) (https://bit.ly/3O4pZ5o) • 200mg high molecular weight hyaluronic acid (https://bit.ly/3P0Z4c2) • 2,400mg of Fisetin, on the 1st, 2nd & 3rd of each month (https://bit.ly/3P2rSB0) • 2,400mg of Quercetin, on the 1st, 2nd & 3rd of each month (https://bit.ly/3IzulAy) • 81mg of aspirin (https://bit.ly/3uFjtem) • 800mg SIRT6 Activator • 600mg DIM Links: https://pubmed.ncbi.nlm.nih.gov/36198293/ https://www.cell.com/cell-metabolism/pdfExtended/S1550-4131(22)00397-7 https://europepmc.org/article/med/36198293 https://plu.mx/plum/a/?doi=10.1016/j.cmet.2022.09.007 https://www.cell.com/cell-metabolism/pdfExtended/S1550-4131(22)00344-8 https://www.pnas.org/doi/full/10.1073/pnas.1008734107 https://onlinelibrary.wiley.com/doi/full/10.1111/jne.12886 https://pubmed.ncbi.nlm.nih.gov/28975706/ Until now, very few studies have actually investigated precisely why late-night eating is linked to greater body weight. This recent study set out to add to this deficit. Researchers found that eating four hours later than normal actually changed many of the physiological and molecular mechanisms in our body that in turn promote weight gain. This work adds to other recently published work which has found that eating earlier in the day is more beneficial for both appetite and weight contrOL. To conduct their study, the researchers had 16 participants follow two different meal schedules, each for a period of six days in total. The first protocol had participants eat their meals early in the day with the last meal consumed approximately six hours and 40 minutes before bedtime. So, for a bedtime of 10pm, that would mean not eating after 3.20 in the afternoon. The second protocol had participants eat all of their daily meals approximately four hours later. So for a 10pm bed time, that would mean not eating after 7.20 in the evening. The study was conducted in a controlled lab environment. This ensured that the participants in each group consumed an identical diet; all of their meals were evenly spaced, with around four hours between each sitting. To understand how late eating affected the body, the researchers specifically looked at three different measures which are associated with weight gain: o The influence of appetite o The impact of eating time on energy expenditure (calories burned), and o Molecular changes from fat tissue. The participants’ appetite was measured throughout using two techniques. The first technique, a more subject method, had the participants rate their feelings of hunger throughout the day. The second technique was collecting blood samples to look at the levels of appetite-regulating hormones in participants' blood. These hormones were leptin (which helps us feel full) and ghrelin (which makes us feel hungry). These hormones were assessed hourly, over a 24 hour period, during the third and sixth day of each trial. To assess the effect of meal timing on daily energy expenditure, a technique called "indirect calorimetry" was used. This measures both the amount of oxygen a person uses alongside the amount of carbon dioxide they produce. This helps researchers estimate how many calories a person's body uses throughout a normal day. DISCLAIMER: This video and description contain discount codes, which means that if you use the code, I will receive a small commission. FAIR-USE COPYRIGHT DISCLAIMER Copyright Disclaimer Under Section 107 of the Copyright Act 1976, allowance is made for "fair use" for purposes such as criticism, commenting, news reporting, teaching, scholarship, and research. Fair use is a use permitted by copyright statute that might otherwise be infringing. Non-profit, educational, or personal use tips the balance in favor of fair use. #HealthyDiet #HealthyLifestyle #LongevityDiet

What is this antiaging wonder drug? Let's see how, when used off label it can help many people in many ways. Renue by Science 10% Discount Code: MYNMN (https://renuebyscience.com/?rfsn=5692699.331801&coupon-code=MYNMN) Renue by Science 15% Subscription Service Discount Code: MYNMNSUB DoNotAge.org 10% Discount Code: MYNMN (https://bit.ly/2VBDgNt) I hope you enjoy my content and find it interesting or informative, if so, please consider supporting the channel by using one of the links below: * Buy me a Kofi: https://ko-fi.com/mynmnexperiment * Patreon: https://bit.ly/3hhfjl5 * SubscribeStar: https://bit.ly/3psYo23 My Current Anti-Aging Protocol: • 1.5 grams of NMN (https://bit.ly/3c2Fxt8) • 1.5 grams of Trans-resveratrol (Tue, Thu & Sat) (https://bit.ly/3yxeqy2) • 500mg Metformin • 1.5 grams of TMG (https://bit.ly/3oe1Ted) • 5,000 IU (International Units) of vitamin D3 (https://bit.ly/3P32hYH) • 120 mcg (micrograms) of vitamin K2 (Mk 7) (https://bit.ly/3PhkBgn) • 250mg Magnesium (L-Threonate) (https://bit.ly/3O4pZ5o) • 200mg high molecular weight hyaluronic acid (https://bit.ly/3P0Z4c2) • 2,400mg of Fisetin, on the 1st, 2nd & 3rd of each month (https://bit.ly/3P2rSB0) • 2,400mg of Quercetin, on the 1st, 2nd & 3rd of each month (https://bit.ly/3IzulAy) • 81mg of aspirin (https://bit.ly/3uFjtem) • 800mg SIRT6 Activator • 600mg DIM Links: https://www.healio.com/news/endocrinology/20170207/beyond-diabetes-metformin-may-prove-to-be-a-wonder-drug https://pubmed.ncbi.nlm.nih.gov/31405774/ https://www.ncbi.nlm.nih.gov/books/NBK518983/#:~:text=Metformin%20also%20has%20several%20non,polycystic%20ovary%20syndrome%20(PCOS). https://www.health.harvard.edu/blog/is-metformin-a-wonder-drug-202109222605 https://clinicaltrials.gov/ct2/show/NCT02432287 https://pubmed.ncbi.nlm.nih.gov/24720592/ https://www.ahajournals.org/doi/10.1161/circ.144.suppl_1.9819 https://www.primary-care-diabetes.com/article/S1751-9918(18)30013-5/fulltext https://honehealth.com/edge/health/benefits-of-metformin/ https://diatribe.org/can-miracle-drug-metformin-also-help-you-lose-weight https://www.uptodate.com/contents/metformin-for-treatment-of-the-polycystic-ovary-syndrome/print https://www.healthline.com/health/diabetes/metformin-weight-loss https://www.researchgate.net/publication/323631830_Update_on_off_label_use_of_metformin_for_obesity https://www.healthline.com/health/diabetes/diabetes-drug-aging Metformin, a medication designed to control diabetes, has of late become the controversial darling of the health-conscious internet elite, who have been attracted by preliminary research suggesting it may help promote longevity, reduce dementia and prevent a whole host of other medical conditions, most recently added to the list is that of long COVID. With origins that date back to Medieval Europe, metformin has been used for decades as a powerful tool to lower blood sugar in people who already have diabetes. In those patients, it also offers cardiovascular benefits and has resulted in significant weight loss. Now it is increasing in popularity for use in conditions that have nothing to do with diabetes. Intrigued by early studies and promotion on platforms such as TikTok and Instagram, and on health-focused blogs, vlogs and websites, people have now started seeking "off-label" prescriptions for metformin. So, off label is using a drug for a different condition, and/or at a different dosage, than it had been originally approved for by the FDA. But experts urge caution, saying there isn't enough data available yet to start recommending daily dosages of these "off-label" prescriptions. Dr. Peter Chin-Hong of the University of California, San Francisco, when citing lack of extensive research, said "I'd be very wary about using metformin off-label at this point, the evidence has to be really strong if you take a drug for a particular indication in which there's not a lot of good data."  Stanford University endocrinologist, Dr. Marilyn Tan MD said: ‘While it's unlikely to do harm’ - “Certainly, a lot of young healthy people are looking into taking it with hopes of kind of optimizing their health and 'biohacking' to improve their longevity down the line. There's also no proven benefit from any randomized controlled trial in terms of anti-aging effects…It's not FDA-approved for any of these other indications." DISCLAIMER: This video and description contain discount codes, which means that if you use the code, I will receive a small commission. FAIR-USE COPYRIGHT DISCLAIMER Copyright Disclaimer Under Section 107 of the Copyright Act 1976, allowance is made for "fair use" for purposes such as criticism, commenting, news reporting, teaching, scholarship, and research. Fair use is a use permitted by copyright statute that might otherwise be infringing. Non-profit, educational, or personal use tips the balance in favor of fair use. #GoatsRue #Glucophage #FrenchLilac

This week’s giveaway is two containers of their RENUE Face Serum with Liposomal Glutathione, Vitamin C, NAD⁺, NMN, and NR. As always this is 3rd party tested for purity and heavy meats and is produced in an FDA approved facility, two containers would normally sell for $115.90. Renue by Science 10% Discount Code: MYNMN (https://renuebyscience.com/?rfsn=5692699.331801&coupon-code=MYNMN) Renue by Science 15% Subscription Service Discount Code: MYNMNSUB I hope you enjoy my content and find it interesting or informative, if so, please consider supporting the channel by using one of the links below: * Buy me a Kofi: https://ko-fi.com/mynmnexperiment * Patreon: https://bit.ly/3hhfjl5 * SubscribeStar: https://bit.ly/3psYo23 My Current Anti-Aging Protocol: • 1.5 grams of NMN (https://bit.ly/3c2Fxt8) • 1.5 grams of Trans-resveratrol (Tue, Thu & Sat) (https://bit.ly/3yxeqy2) • 500mg Metformin • 1.5 grams of TMG (https://bit.ly/3oe1Ted) • 5,000 IU (International Units) of vitamin D3 (https://bit.ly/3P32hYH) • 120 mcg (micrograms) of vitamin K2 (Mk 7) (https://bit.ly/3PhkBgn) • 250mg Magnesium (L-Threonate) (https://bit.ly/3O4pZ5o) • 200mg high molecular weight hyaluronic acid (https://bit.ly/3P0Z4c2) • 2,400mg of Fisetin, on the 1st, 2nd & 3rd of each month (https://bit.ly/3P2rSB0) • 2,400mg of Quercetin, on the 1st, 2nd & 3rd of each month (https://bit.ly/3IzulAy) • 81mg of aspirin (https://bit.ly/3uFjtem) • 800mg SIRT6 Activator • 600mg DIM DISCLAIMER: The Video Content has been made available for informational and educational purposes only. The video creator does not make any representation or warranties with respect to the accuracy, applicability, fitness, or completeness of the Video Content. The Video Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. The video creator hereby disclaims any and all liability to any party for any direct, indirect, implied, punitive, special, incidental or other consequential damages arising directly or indirectly from any use of the Video Content, which is provided as is, and without warranties. Best GLUTATHIONE brand in 2023, best GLUTATHIONE supplement 2023, best GLUTATHIONE supplements reviews, best GLUTATHIONE, best GLUTATHIONE supplement, best GLUTATHIONE supplement on the market, best GLUTATHIONE 2023, GLUTATHIONE Human Trial, Best antioxidant brand in 2023, best antioxidant supplement 2023, best antioxidant supplements reviews, best SENOLYTIC, best SENOLYTIC supplement, best antioxidant supplement on the market, best antioxidant 2023, antioxidant Human Trial, DoNotAge.org, Do Not Age, Renue by Science, Renue by Science reviews DISCLAIMER: This video and description contain discount codes, which means that if you use the code, I will receive a small commission. FAIR-USE COPYRIGHT DISCLAIMER Copyright Disclaimer Under Section 107 of the Copyright Act 1976, allowance is made for "fair use" for purposes such as criticism, commenting, news reporting, teaching, scholarship, and research. Fair use is a use permitted by copyright statute that might otherwise be infringing. Non-profit, educational, or personal use tips the balance in favor of fair use. #RenueByScience #Glutathione #Giveaway

the results of a 20-year study out of Sweden has shown that if you are worried about the risk of dementia, a well-loved longevity diet, alone, may not be enough to mitigate the risk. DoNotAge.org 10% Discount Code: MYNMN (https://bit.ly/2VBDgNt) Renue by Science 10% Discount Code: MYNMN (https://renuebyscience.com/?rfsn=5692699.331801&coupon-code=MYNMN) Renue by Science 15% Subscription Service Discount Code: MYNMNSUB I hope you enjoy my content and find it interesting or informative, if so, please consider supporting the channel by using one of the links below: * Buy me a Kofi: https://ko-fi.com/mynmnexperiment * Patreon: https://bit.ly/3hhfjl5 * SubscribeStar: https://bit.ly/3psYo23 My Current Anti-Aging Protocol: • 1.5 grams of NMN (https://bit.ly/3c2Fxt8) • 1.5 grams of Trans-resveratrol (Tue, Thu & Sat) (https://bit.ly/3yxeqy2) • 500mg Metformin • 1.5 grams of TMG (https://bit.ly/3oe1Ted) • 5,000 IU (International Units) of vitamin D3 (https://bit.ly/3P32hYH) • 120 mcg (micrograms) of vitamin K2 (Mk 7) (https://bit.ly/3PhkBgn) • 250mg Magnesium (L-Threonate) (https://bit.ly/3O4pZ5o) • 200mg high molecular weight hyaluronic acid (https://bit.ly/3P0Z4c2) • 2,400mg of Fisetin, on the 1st, 2nd & 3rd of each month (https://bit.ly/3P2rSB0) • 2,400mg of Quercetin, on the 1st, 2nd & 3rd of each month (https://bit.ly/3IzulAy) • 81mg of aspirin (https://bit.ly/3uFjtem) • 800mg SIRT6 Activator • 600mg DIM Links: https://n.neurology.org/content/early/2022/10/12/WNL.0000000000201336 https://jamanetwork.com/journals/jama/fullarticle/2727449 https://pubmed.ncbi.nlm.nih.gov/36224029/#:~:text=Discussion%3A%20In%20this%2020%2Dyear,%2C%20VaD%20or%20AD%2Dpathology. https://portal.research.lu.se/en/publications/association-between-dietary-habits-in-midlife-with-dementia-incid https://www.linksmedicus.com/news/cohort-study-association-dietary-habits-midlife-dementia-incidence-20-year-period/ According to a 20-year study out of Sweden the much loved "Mediterranean diet" does not lower the odds of developing dementia. Previous studies of the potential cognitive benefits of the so-called Mediterranean diet, broadly defined as a diet rich in vegetables, fruit, fish, and unsaturated fats, such as olive oil; also known for being low in dairy, red meats, and saturated fats, have turned up mixed results; this is according to the National Institutes of Health's National Institute on Aging. Two 2019 studies in the journal JAMA that included thousands of people and decades of follow-up found no evidence that the Mediterranean diet reduces dementia risk, or that that diet quality affects dementia risk, broadly. This new Swedish study casts further doubt on the diet's brain-bolstering benefits. Dr. Isabelle Glans, first author of the study, and member of the Clinical Memory Research Unit at the Lund University, Sweden, set out in an email to Live Science wrote "We did not find any association between either conventional dietary habits or adherence to a Mediterranean diet and subsequent incidence of dementia." These findings, which align with those found in prior studies of similar size and length, were published on the 12th of October in the journal Neurology. That said, similar to many previous studies, the research relied on self-reported dietary data from participants, which may not be wholly accurate and can somewhat skew the interpretation of the results. Physiologist Ancel Keys and biochemist Margaret Keys, a husband-wife duo, derived the Mediterranean diet from Ancel's influential research on the link between men's diets and their risk of heart attack and stroke. The research suggested that diets low in saturated fat protect against cardiovascular disease, and Ancel and Margaret drew loose inspiration from Greek, Italian, and other Mediterranean cuisines to write their popular diet books, this is according to The Conversation. A quick insight into Ancel Keys, if you aren’t aware of this charlatan’s history. His Lipid hypothesis (still not proved) was based on a study of the saturated fat consumption in these countries, which showed a direct correlation between saturated fat consumption and heart disease. What he omitted from his final report was that he had in fact studied more than 20 countries and when you add that data, there is no correlation whatsoever. DISCLAIMER: This video and description contain discount codes, which means that if you use the code, I will receive a small commission. FAIR-USE COPYRIGHT DISCLAIMER Copyright Disclaimer Under Section 107 of the Copyright Act 1976, allowance is made for "fair use" for purposes such as criticism, commenting, news reporting, teaching, scholarship, and research. Fair use is a use permitted by copyright statute that might otherwise be infringing. Non-profit, educational, or personal use tips the balance in favor of fair use. #LongevityDiet #antiagingdiet #Healthylifestyle

Let’s take a look at my biological age, 43 months years after starting My NMN Experiment. Renue by Science 10% Discount Code: MYNMN (https://renuebyscience.com/?rfsn=5692699.331801&coupon-code=MYNMN) Renue by Science 15% Subscription Service Discount Code: MYNMNSUB DoNotAge.org 10% Discount Code: MYNMN (https://bit.ly/2VBDgNt) I hope you enjoy my content and find it interesting or informative, if so, please consider supporting the channel by using one of the links below: * Buy me a Kofi: https://ko-fi.com/mynmnexperiment * Patreon: https://bit.ly/3hhfjl5 * SubscribeStar: https://bit.ly/3psYo23 My Current Anti-Aging Protocol: • 1.5 grams of NMN (https://bit.ly/3c2Fxt8) • 1.5 grams of Trans-resveratrol (Tue, Thu & Sat) (https://bit.ly/3yxeqy2) • 500mg Metformin • 1.5 grams of TMG (https://bit.ly/3oe1Ted) • 5,000 IU (International Units) of vitamin D3 (https://bit.ly/3P32hYH) • 120 mcg (micrograms) of vitamin K2 (Mk 7) (https://bit.ly/3PhkBgn) • 250mg Magnesium (L-Threonate) (https://bit.ly/3O4pZ5o) • 200mg high molecular weight hyaluronic acid (https://bit.ly/3P0Z4c2) • 2,400mg of Fisetin, on the 1st, 2nd & 3rd of each month (https://bit.ly/3P2rSB0) • 2,400mg of Quercetin, on the 1st, 2nd & 3rd of each month (https://bit.ly/3IzulAy) • 81mg of aspirin (https://bit.ly/3uFjtem) • 800mg SIRT6 Activator • 600mg DIM DISCLAIMER: The Video Content has been made available for informational and educational purposes only. The video creator does not make any representation or warranties with respect to the accuracy, applicability, fitness, or completeness of the Video Content. The Video Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. The video creator hereby disclaims any and all liability to any party for any direct, indirect, implied, punitive, special, incidental or other consequential damages arising directly or indirectly from any use of the Video Content, which is provided as is, and without warranties. Discovered by David Sinclair PhD, NMN or Nicotinamide Mononucleotide is the pre-cursor to NAD+ (Nicotinamide Adenine Dinucleotide), NAD is found in nearly all our living cells. NAD is essential for sustaining life. Dr. David Sinclair (a professor at Harvard Medical School) once said if we suddenly didn’t have NAD we would be dead within eight seconds.’ Unfortunately, as we age our NAD levels drastically decline, clinical studies have shown that by age of 50 a typical person could have half the NAD+ they did in their youth and by the age of 80 our NAD+ (Nicotinamide Adenine Dinucleotide) levels drop to around 1% to 10% of those enjoyed in our youth. NAD is biologically unstable, which makes it unsuitable for oral supplementation. Fortunately, it is easy to restore our cellular NAD levels using NMN (Nicotinamide Mononucleotide) or NR (Nicotinamide Riboside), which convert to NAD when it is in the cell. These NAD boosting supplements can be purchased from reputable companies such as Do Not Age, Renue by Science and Pro-health Longevity, however there are many unscrupulous companies selling fake NMN, so buyer beware. Dr. David Sinclair confirms that a fascinating aspect of NAD+ is its dual role in protecting against factors that age us. This includes mitigating chemical stress, inflammation, DNA damage and failing mitochondria; all conditions associated with aging. In other words, while a decline in NAD+ levels may negatively influence lifespan and Healthspan (health-span), so restoring NAD+ is increasingly being viewed as a scientific way to promote longevity and a way to combat the diseases of aging too. A rigorous scientific review of NAD+ reveals that its longevity benefits arise from eight different, but interrelated, functions. In 2013 a scientific study; 2-year old mice were tested for muscle wastage, insulin resistance and inflammation, all are, on humans used as indicators of the aging process, they were then given NMN (Nicotinamide Mononucleotide) for 1 week. In all cases, after only 1 week the 2-year old mice were reflecting the expected findings of 6-month old mice in the areas of muscle wastage, insulin resistance and inflammation. DISCLAIMER: This video and description contain discount codes, which means that if you use the code, I will receive a small commission. FAIR-USE COPYRIGHT DISCLAIMER Copyright Disclaimer Under Section 107 of the Copyright Act 1976, allowance is made for "fair use" for purposes such as criticism, commenting, news reporting, teaching, scholarship, and research. Fair use is a use permitted by copyright statute that might otherwise be infringing. Non-profit, educational, or personal use tips the balance in favor of fair use. #DavidSinclair #RenueByScience #donotage

this week’s MEGA offer Is 366 x 400mg Fisetin capsules, which would normally sell for a whopping $500. DoNotAge.org 10% Discount Code: MYNMN (https://bit.ly/2VBDgNt) I hope you enjoy my content and find it interesting or informative, if so, please consider supporting the channel by using one of the links below: * Buy me a Kofi: https://ko-fi.com/mynmnexperiment * Patreon: https://bit.ly/3hhfjl5 * SubscribeStar: https://bit.ly/3psYo23 My Current Anti-Aging Protocol: • 1.5 grams of NMN (https://bit.ly/3c2Fxt8) • 1.5 grams of Trans-resveratrol (Tue, Thu & Sat) (https://bit.ly/3yxeqy2) • 500mg Metformin • 1.5 grams of TMG (https://bit.ly/3oe1Ted) • 5,000 IU (International Units) of vitamin D3 (https://bit.ly/3P32hYH) • 120 mcg (micrograms) of vitamin K2 (Mk 7) (https://bit.ly/3PhkBgn) • 250mg Magnesium (L-Threonate) (https://bit.ly/3O4pZ5o) • 200mg high molecular weight hyaluronic acid (https://bit.ly/3P0Z4c2) • 2,400mg of Fisetin, on the 1st, 2nd & 3rd of each month (https://bit.ly/3P2rSB0) • 2,400mg of Quercetin, on the 1st, 2nd & 3rd of each month (https://bit.ly/3IzulAy) • 81mg of aspirin (https://bit.ly/3uFjtem) • 800mg SIRT6 Activator • 600mg DIM DISCLAIMER: The Video Content has been made available for informational and educational purposes only. The video creator does not make any representation or warranties with respect to the accuracy, applicability, fitness, or completeness of the Video Content. The Video Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. The video creator hereby disclaims any and all liability to any party for any direct, indirect, implied, punitive, special, incidental or other consequential damages arising directly or indirectly from any use of the Video Content, which is provided as is, and without warranties. Best Fisetin Brand 2023,Best Fisetin Supplement 2023,Fisetin Human Trial, Dr. David Sinclair,DoNotAge.org,DoNotAge,Renue by Science,Renue by Science reviews,Renue by Science Fisetin,ProHealth Longevity,ProHealth Longevity reviews,ProHealth longevity Fisetin,Fisetin,Fisetin Powder,Fisetin Supplement,where to buy Fisetin,Fisetin side effects,Fisetin Supplement Review,Best Senolytic brand in 2023,best SENOLYTIC supplement 2023, best SENOLYTIC supplements reviews,best SENOLYTIC,best SENOLYTIC supplement on the market,SENOLYTIC Human Trial. DISCLAIMER: This video and description contain discount codes, which means that if you use the code, I will receive a small commission. FAIR-USE COPYRIGHT DISCLAIMER Copyright Disclaimer Under Section 107 of the Copyright Act 1976, allowance is made for "fair use" for purposes such as criticism, commenting, news reporting, teaching, scholarship, and research. Fair use is a use permitted by copyright statute that might otherwise be infringing. Non-profit, educational, or personal use tips the balance in favor of fair use. #donotage #fisetin #giveaways

although extremely popular at the moment, cold water immersion does have some very substantial risks, risks all too often ignored by the proppants of it use. Renue by Science 10% Discount Code: MYNMN (https://renuebyscience.com/?rfsn=5692699.331801&coupon-code=MYNMN) Renue by Science 15% Subscription Service Discount Code: MYNMNSUB DoNotAge.org 10% Discount Code: MYNMN (https://bit.ly/2VBDgNt) I hope you enjoy my content and find it interesting or informative, if so, please consider supporting the channel by using one of the links below: * Buy me a Kofi: https://ko-fi.com/mynmnexperiment * Patreon: https://bit.ly/3hhfjl5 * SubscribeStar: https://bit.ly/3psYo23 My Current Anti-Aging Protocol: • 1.5 grams of NMN (https://bit.ly/3c2Fxt8) • 1.5 grams of Trans-resveratrol (Tue, Thu & Sat) (https://bit.ly/3yxeqy2) • 500mg Metformin • 1.5 grams of TMG (https://bit.ly/3oe1Ted) • 5,000 IU (International Units) of vitamin D3 (https://bit.ly/3P32hYH) • 120 mcg (micrograms) of vitamin K2 (Mk 7) (https://bit.ly/3PhkBgn) • 250mg Magnesium (L-Threonate) (https://bit.ly/3O4pZ5o) • 200mg high molecular weight hyaluronic acid (https://bit.ly/3P0Z4c2) • 2,400mg of Fisetin, on the 1st, 2nd & 3rd of each month (https://bit.ly/3P2rSB0) • 2,400mg of Quercetin, on the 1st, 2nd & 3rd of each month (https://bit.ly/3IzulAy) • 81mg of aspirin (https://bit.ly/3uFjtem) • 800mg SIRT6 Activator • 600mg DIM Links: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730683/ https://www.coldwatersafety.org/the-danger https://medicalxpress.com/news/2022-09-experts-cold-immersion-significant-responsibly.html https://hunterandgatherfoods.com/blogs/real-food-lifestyle/unfinished-dangers-of-cold-water-therapy https://medicalxpress.com/news/2022-01-cold-water-acclimatize-temperature.html https://www.morozkoforge.com/post/ice-bath-safety https://www.medicalnewstoday.com/articles/327461 https://theconversation.com/cold-showers-a-scientist-explains-if-they-are-as-good-for-you-as-wim-hof-the-iceman-suggests-181678 Jumping into icy cold water in the dead of winter might seem like a crazy idea, but the so-called “polar bear plunge” has become a popular activity, often paired with raising money for charity. Arguably the most well-known proponent of this is Wim Hof, indeed he is known as the ice man. But the benefits of cold-water immersion have been widely proclaimed by trusted figures in the health and wellness space; personalities such as Rhonda Patrick and Andrew Huberman. But the risks, and there are real risks, are very rarely touched upon.  The practice of cold therapy is based on the belief that exposing the body to cold water and air may strengthen the immune system, and improve cardiovascular health. Hollywood actor Chris Hemsworth of "Thor" fame helped promote the idea when he took an Arctic swim without a wetsuit as part of National Geographic's "Limitless" television series. Although a popular activity, the actual scientific evidence supporting the health benefits of cold therapy remains scant. Experts caution that for some people, shocking the body with cold water could do more harm than good, even at less-than-frigid temperatures. The National Center for Cold Water Safety warns that sudden immersion in water under 60 degrees Fahrenheit (15 degrees Centigrade) can kill a person in less than a minute – that is quite a sobering fact. Dr. Jorge Plutzky, director of preventive cardiology at Brigham and Women's Hospital in Boston said "Cold shock can be dangerous...Whether there are health benefits or not - is not clear - and has not been established." Plunging your body into cold water triggers a sudden, rapid increase in breathing, heart rate and blood pressure known as the cold shock response. This can cause a person to drown within seconds if they involuntarily gasp while their head is submerged. The shock also places stress on the heart and makes it work harder; within minutes the sudden loss of body heat begins causing other problems. Dr. Plutzky stated that ‘Blood rushes away from the extremities to the body's core to protect vital organs, this leaves the arms and legs without good circulation, which can lead to a loss of strength and coordination. The rapid loss of heat also can lead to hypothermia, making it harder to think clearly or move well. Being immersed in cold water triggers hypothermia faster than just being out in the cold. DISCLAIMER: This video and description contain discount codes, which means that if you use the code, I will receive a small commission. FAIR-USE COPYRIGHT DISCLAIMER Copyright Disclaimer Under Section 107 of the Copyright Act 1976, allowance is made for "fair use" for purposes such as criticism, commenting, news reporting, teaching, scholarship, and research. Fair use is a use permitted by copyright statute that might otherwise be infringing. Non-profit, educational, or personal use tips the balance in favor of fair use. #WimHof #ColdShower #IceMan

A new study out of China has tested 5 different compounds and found that 2 of them did actually, as they say in the paper “significantly diminished the predicted age.” Renue by Science 10% Discount Code: MYNMN (https://renuebyscience.com/?rfsn=5692699.331801&coupon-code=MYNMN) Renue by Science 15% Subscription Service Discount Code: MYNMNSUB DoNotAge.org 10% Discount Code: MYNMN (https://bit.ly/2VBDgNt) I hope you enjoy my content and find it interesting or informative, if so, please consider supporting the channel by using one of the links below: *Buy me a Kofi: https://ko-fi.com/mynmnexperiment *Patreon: https://bit.ly/3hhfjl5 *SubscribeStar: https://bit.ly/3psYo23 My Current Anti-Aging Protocol: • 1.5 grams of NMN (https://bit.ly/3c2Fxt8) • 1.5 grams of Trans-resveratrol (Tue, Thu & Sat) (https://bit.ly/3yxeqy2) • 500mg Metformin • 1.5 grams of TMG (https://bit.ly/3oe1Ted) • 5,000 IU (International Units) of vitamin D3 (https://bit.ly/3P32hYH) • 120 mcg (micrograms) of vitamin K2 (Mk 7) (https://bit.ly/3PhkBgn) • 250mg Magnesium (L-Threonate) (https://bit.ly/3O4pZ5o) • 200mg high molecular weight hyaluronic acid (https://bit.ly/3P0Z4c2) • 2,400mg of Fisetin, on the 1st, 2nd & 3rd of each month (https://bit.ly/3P2rSB0) • 2,400mg of Quercetin, on the 1st, 2nd & 3rd of each month (https://bit.ly/3IzulAy) • 81mg of aspirin (https://bit.ly/3uFjtem) • 800mg SIRT6 Activator • 600mg DIM Links: https://pubmed.ncbi.nlm.nih.gov/36382193/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9619353/ https://www.biorxiv.org/content/10.1101/2022.01.17.476558v1 https://www.sciencedirect.com/science/article/pii/S2001037022004688 United Nations, Department of Economic and Social Affairs, Population Division (2019). World Population Prospects 2019: Highlights. ST/ESA/SER.A/423. The world has a rapidly expanding population of people over age 65, this has, of late, been dubbed the “silver tsunami.” Life expectancy has increased dramatically in the past 150 years. It is expected that worldwide 1.5 billion people aged 65 years or over will outnumber adolescents and the youth aged 15 to 24 years (1.3 billion) in 2050. People aged 65 years and older are experiencing the aging process, characterized by progressive impairment and loss of physiological integrity and function, leading to an increased vulnerability to death. It is without question that the world is facing an aging challenge. Currently, scientists in the aging research field continue to gauge and compare how fast people age with newly devised aging clocks to enable research on the most effective means to combat the ravages of aging. This will require a standardized measurement of aging, many in the aging research field are now turning toward transcript-mics – measuring RNA sequences as an indicator of gene activity. By using transcriptomics to assess people’s pace of aging, we can now compare compounds that have previously been shown to counter aging in animal studies. Published in the journal Computational and Structural Biotechnology, HongWei Ouyang PhD and his colleagues from Zhejiang University School of Medicine in China have generated a transcriptomics-based aging clock. Using their clock, they demonstrated that applying NMN or metformin to blood samples reduces predicted age. The team identified that slow-aging individual’s exhibit blood immune cell levels indicative of less inflammation than fast-aging individuals. The development of this new aging clock may contribute to anti-aging scientists’ quest for a standardized means to measure biological aging, which can then be used for comparing compounds that can potentially increase the years that we live in good health – known as healthspan. The genes coded in our DNA are transcribed to mRNA before being translated into a protein, so by measuring mRNA levels gene activity can be assessed. The “transcriptome” encompasses the most active genes at a given time. The researchers analyzed the blood cell transcriptomes of 505 individuals aged between 18 and 68 and found that 1,138 mRNA transcripts had significantly changed with age. Using statistical analyses, the team used the mRNA transcript levels to determine gene activity and predict biological age, this being a person’s physiological age in relation to their age-matched counterparts. In doing so, Dr. Ouyang and his colleagues found that people could be divided into three populations. DISCLAIMER: This video and description contain discount codes, which means that if you use the code, I will receive a small commission. FAIR-USE COPYRIGHT DISCLAIMER Copyright Disclaimer Under Section 107 of the Copyright Act 1976, allowance is made for "fair use" for purposes such as criticism, commenting, news reporting, teaching, scholarship, and research. Fair use is a use permitted by copyright statute that might otherwise be infringing. Non-profit, educational, or personal use tips the balance in favor of fair use. #Glucophage #Metformin #NicotinamideMononucleotide

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Does the position that you use to go to sleep and then the position that you adopt most throughout the night have an effect on the quality of your sleep? DoNotAge.org 10% Discount Code: MYNMN (https://bit.ly/2VBDgNt) Renue by Science 10% Discount Code: MYNMN (https://renuebyscience.com/?rfsn=5692699.331801&coupon-code=MYNMN) Renue by Science 15% Subscription Service Discount Code: MYNMNSUB I hope you enjoy my content and find it interesting or informative, if so, please consider supporting the channel by using one of the links below: *Buy me a Kofi: https://ko-fi.com/mynmnexperiment *Patreon: https://bit.ly/3hhfjl5 *SubscribeStar: https://bit.ly/3psYo23 My Current Anti-Aging Protocol: • 1.5 grams of NMN (https://bit.ly/3c2Fxt8) • 1.5 grams of Trans-resveratrol (Tue, Thu & Sat) (https://bit.ly/3yxeqy2) • 500mg Metformin • 1.5 grams of TMG (https://bit.ly/3oe1Ted) • 5,000 IU (International Units) of vitamin D3 (https://bit.ly/3P32hYH) • 120 mcg (micrograms) of vitamin K2 (Mk 7) (https://bit.ly/3PhkBgn) • 250mg Magnesium (L-Threonate) (https://bit.ly/3O4pZ5o) • 200mg high molecular weight hyaluronic acid (https://bit.ly/3P0Z4c2) • 2,400mg of Fisetin, on the 1st, 2nd & 3rd of each month (https://bit.ly/3P2rSB0) • 2,400mg of Quercetin, on the 1st, 2nd & 3rd of each month (https://bit.ly/3IzulAy) • 81mg of aspirin (https://bit.ly/3uFjtem) • 800mg SIRT6 Activator • 600mg DIM Most people prefer to sleep on their side. This is good, as generally those who lie on their backs are more likely to be poor sleepers or have breathing difficulties during the night. Most people tend to move around quite a lot during the night. One study of 664 sleepers found, on average, that participants spent about 54% of their time in bed sleeping on their side, about 37% on their back, and about 7% on their front. Males (especially those under the age of 35) tend to be most restless, with more position shifts, and arm, thigh, and upper-back movements during the night than any other group. Changing position as you sleep may not be a bad thing; allowing your body to move during the night is generally a good idea. During sleep, your body will keep track of any pain or discomfort and adjust your position accordingly. This is why we usually avoid developing bedsores (or pressure ulcers) in everyday life. If you find you can't move because your partner, or child, or dog is taking up too much room in the bed, consider switching sides or getting a larger bed. And for those that still use sheets and blankets, don't tuck yourself in too tightly; give yourself some room to move around on either side. The truth is that there is no quality research providing clear evidence for an "optimal sleep position." Your age, your weight, the sleep environment, your sleep partner or partners, your daily activities, pregnancy etc. all play a role in which sleep position is best for your body. We should all be able to find a position that helps us get a good night's sleep, and one that avoids us waking up in any pain. And fitness trackers can take the guess work out of this process. Even when you find the potion that affords you the best night’s sleep, some layouts are better than others. In one study, people who rested in a position where there is a rotation of the spine (such as the unsupported side position), woke up with more pain in the morning. Nonetheless, although some forms of side-sleeping may cause a bit of load on the spine, studies show that side positions, in general, are still better than the other options i.e. on your back or front. A lack of support for the head and neck during sleep has been found to severely impact spine alignment, and can cause muscle problems such as neck pain, shoulder pain and muscle stiffness. Surprisingly, the actual pillow material does not appear to affect the spine. It is in fact the shape and the height that really matters. A U-shaped pillow may help you have a longer night's sleep, and a roll-shaped pillow can reduce morning and bedtime discomfort. Unfortunately, science has not given us an answer on what is the optimal mattress. With everyone sleeping differently, this would be hard to compare over the long term and come up with one definitive recommendation. However, there are bad mattresses. If your bed is sagging, has lost its firmness, develops noisy springs, or shows clear signs of wear and tear, you should consider changing your mattress. DISCLAIMER: This video and description contain discount codes, which means that if you use the code, I will receive a small commission. FAIR-USE COPYRIGHT DISCLAIMER Copyright Disclaimer Under Section 107 of the Copyright Act 1976, allowance is made for "fair use" for purposes such as criticism, commenting, news reporting, teaching, scholarship, and research. Fair use is a use permitted by copyright statute that might otherwise be infringing. Non-profit, educational, or personal use tips the balance in favor of fair use. #Sleep #Sleepy #SleepPosition

A new study out of the University of Michigan has shown that one strength marker, if not optimal, has a clear link with faster biological aging. Renue by Science 10% Discount Code: MYNMN (https://renuebyscience.com/?rfsn=5692699.331801&coupon-code=MYNMN) Renue by Science 15% Subscription Service Discount Code: MYNMNSUB DoNotAge.org 10% Discount Code: MYNMN (https://bit.ly/2VBDgNt) I hope you enjoy my content and find it interesting or informative, if so, please consider supporting the channel by using one of the links below: *Buy me a Kofi: https://ko-fi.com/mynmnexperiment *Patreon: https://bit.ly/3hhfjl5 *SubscribeStar: https://bit.ly/3psYo23 My Current Anti-Aging Protocol: • 1.5 grams of NMN (https://bit.ly/3c2Fxt8) • 1.5 grams of Trans-resveratrol (Tue, Thu & Sat) (https://bit.ly/3yxeqy2) • 500mg Metformin • 1.5 grams of TMG (https://bit.ly/3oe1Ted) • 5,000 IU (International Units) of vitamin D3 (https://bit.ly/3P32hYH) • 120 mcg (micrograms) of vitamin K2 (Mk 7) (https://bit.ly/3PhkBgn) • 250mg Magnesium (L-Threonate) (https://bit.ly/3O4pZ5o) • 200mg high molecular weight hyaluronic acid (https://bit.ly/3P0Z4c2) • 2,400mg of Fisetin, on the 1st, 2nd & 3rd of each month (https://bit.ly/3P2rSB0) • 2,400mg of Quercetin, on the 1st, 2nd & 3rd of each month (https://bit.ly/3IzulAy) • 81mg of aspirin (https://bit.ly/3uFjtem) • 600mg DIM Links: Flex Bar Video: https://www.youtube.com/watch?v=Jkl5X4qOP70 https://onlinelibrary.wiley.com/doi/10.1002/jcsm.13110 https://www.researchgate.net/figure/Association-between-grip-strength-and-DNA-methylation-age-acceleration-in-the-total-group_fig1_324224736 https://www.ajmc.com/view/what-we-re-reading-climate-resilience-pledge-improving-addiction-care-weak-grip-strength-may-signal-biological-aging Everyone ages at a different pace, birthdays may be the same, but bodies will be different. That's why two 50-year-olds, despite having lived the same number of years, will probably have different biological or epigenetic ages - meaning that a host of intrinsic and extrinsic factors will have caused them to age at varying paces, with different levels of risk for disease and possibly even an early death. Lifestyle choices, such as diet, smoking, sleep and exercise all contribute to accelerating your biological age beyond your chronological age; your birthday age. In other words, your body is aging faster than expected. And for the first time, researchers have found that muscle weakness marked by grip strength, a proxy for overall strength capacity, is associated with accelerated biological age. Specifically, the weaker your grip strength, the older your biological age, according to results published in the Journal of Cachexia (Ka-keks-ia), Sarcopenia and Muscle. Researchers at Michigan Medicine modeled the relationship between the biological age and the grip strength, this was done with 1,274 middle aged and older adults. They used 3 "age acceleration clocks" based on DNA methylation, a process that provides a molecular biomarker and estimator of the pace of aging. The clocks were originally modeled from various studies examining diabetes, cardiovascular disease, cancer, physical disability, Alzheimer's disease, inflammation and early mortality. The results clearly revealed that both older men and women showed a marked association between lower grip strength, and biological age acceleration, across all the DNA methylation clocks. Mark Peterson, PhD, the lead author and Associate Professor of Physical Medicine & Rehabilitation at the University of Michigan said "We've known that muscular strength is a predictor of longevity, and that weakness is a powerful indicator of disease and mortality, but for the first time, we have found strong evidence of a biological link between muscle weakness and actual acceleration in biological age. This suggests that if you maintain your muscle strength across the lifespan, you may be able to protect against many common age-related diseases. We know that smoking, for example, can be a powerful predictor of disease and mortality, but now we know that muscle weakness could be the new smoking." Past studies have shown that low grip strength is an extremely strong predictor of adverse health events. One study found that it is a better predictor of cardiovascular events. DISCLAIMER: This video and description contain discount codes, which means that if you use the code, I will receive a small commission. FAIR-USE COPYRIGHT DISCLAIMER Copyright Disclaimer Under Section 107 of the Copyright Act 1976, allowance is made for "fair use" for purposes such as criticism, commenting, news reporting, teaching, scholarship, and research. Fair use is a use permitted by copyright statute that might otherwise be infringing. Non-profit, educational, or personal use tips the balance in favor of fair use. #Dynamometer #GripStrength #EpigeneticAge #wellness #healthylifestyle #healthyliving #healthy #antiaging #biohacking #healthylife #intermittentfasting

This week’s MEGA offer from DoNotAge is 366 x 500mg capsules of their Apigenin, which would normally sell for a whopping $260. DoNotAge.org 10% Discount Code: MYNMN (https://bit.ly/2VBDgNt) I hope you enjoy my content and find it interesting or informative, if so, please consider supporting the channel by using one of the links below: *Buy me a Kofi: https://ko-fi.com/mynmnexperiment *Patreon: https://bit.ly/3hhfjl5 *SubscribeStar: https://bit.ly/3psYo23 My Current Anti-Aging Protocol: • 1.5 grams of NMN (https://bit.ly/3c2Fxt8) • 1.5 grams of Trans-resveratrol (Tue, Thu & Sat) (https://bit.ly/3yxeqy2) • 500mg Metformin • 1.5 grams of TMG (https://bit.ly/3oe1Ted) • 5,000 IU (International Units) of vitamin D3 (https://bit.ly/3P32hYH) • 120 mcg (micrograms) of vitamin K2 (Mk 7) (https://bit.ly/3PhkBgn) • 250mg Magnesium (L-Threonate) (https://bit.ly/3O4pZ5o) • 200mg high molecular weight hyaluronic acid (https://bit.ly/3P0Z4c2) • 2,400mg of Fisetin, on the 1st, 2nd & 3rd of each month (https://bit.ly/3P2rSB0) • 2,400mg of Quercetin, on the 1st, 2nd & 3rd of each month (https://bit.ly/3IzulAy) • 81mg of aspirin (https://bit.ly/3uFjtem) • 600mg DIM DISCLAIMER: The Video Content has been made available for informational and educational purposes only. The video creator does not make any representation or warranties with respect to the accuracy, applicability, fitness, or completeness of the Video Content. The Video Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. The video creator hereby disclaims any and all liability to any party for any direct, indirect, implied, punitive, special, incidental or other consequential damages arising directly or indirectly from any use of the Video Content, which is provided as is, and without warranties. DISCLAIMER: This video and description contain discount codes, which means that if you use the code, I will receive a small commission. FAIR-USE COPYRIGHT DISCLAIMER Copyright Disclaimer Under Section 107 of the Copyright Act 1976, allowance is made for "fair use" for purposes such as criticism, commenting, news reporting, teaching, scholarship, and research. Fair use is a use permitted by copyright statute that might otherwise be infringing. Non-profit, educational, or personal use tips the balance in favor of fair use. Best Apigenin brand in 2023, best Apigenin supplement 2023, best Apigenin supplements reviews, best Apigenin, best Apigenin supplement, best Apigenin supplement on the market, best Apigenin 2023, Apigenin Human Trial, Dr. David Sinclair,David Sinclair PhD,DoNotAge.org,DoNotAge,Renue by Science, Renue by Science reviews,Renue by Science Apigenin,ProHealth Longevity, ProHealth Longevity reviews,ProHealth longevity Apigenin,Apigenin, Apigenin Powder,Apigenin Supplement,Apigenin Capsules,Apigenin tablets,Cheapest Apigenin Supplement,where to buy Apigenin,Apigenin side effects,Apigenin Supplement Review - #apigenin #donotage #giveaways #livelonger #livelong #Aging #Lifespan #healthspan #weightloss #nutrition #fat #drdavidsinclair #immortal #aging #antiaging #NAD #wellness #healthylifestyle #healthyliving #healthy #antiaging #biohacking #healthylife #intermittentfasting #paleo #healing #selfcare #mindset #organic #wellbeing #epigenetics #guthealth #holistic #detox #functionalmedicine

People who seek medical treatment for obesity and/or an eating disorder do so with the hope their health plan will pay for part of it, but whether it's covered or not, often comes down to a standard that was invented almost 200 years ago by a Belgian mathematician and astronomer as part of his quest to use statistics to define the "average man." DoNotAge.org 10% Discount Code: MYNMN (https://bit.ly/2VBDgNt) Renue by Science 10% Discount Code: MYNMN (https://renuebyscience.com/?rfsn=5692699.331801&coupon-code=MYNMN) Renue by Science 15% Subscription Service Discount Code: MYNMNSUB I hope you enjoy my content and find it interesting or informative, if so, please consider supporting the channel by using one of the links below: *Buy me a Kofi: https://ko-fi.com/mynmnexperiment *Patreon: https://bit.ly/3hhfjl5 *SubscribeStar: https://bit.ly/3psYo23 My Current Anti-Aging Protocol: • 1.5 grams of NMN (https://bit.ly/3c2Fxt8) • 1.5 grams of Trans-resveratrol (Tue, Thu & Sat) (https://bit.ly/3yxeqy2) • 500mg Metformin • 1.5 grams of TMG (https://bit.ly/3oe1Ted) • 5,000 IU (International Units) of vitamin D3 (https://bit.ly/3P32hYH) • 120 mcg (micrograms) of vitamin K2 (Mk 7) (https://bit.ly/3PhkBgn) • 250mg Magnesium (L-Threonate) (https://bit.ly/3O4pZ5o) • 200mg high molecular weight hyaluronic acid (https://bit.ly/3P0Z4c2) • 2,400mg of Fisetin, on the 1st, 2nd & 3rd of each month (https://bit.ly/3P2rSB0) • 2,400mg of Quercetin, on the 1st, 2nd & 3rd of each month (https://bit.ly/3IzulAy) • 81mg of aspirin (https://bit.ly/3uFjtem) • 600mg DIM Many critics say BMI was never meant as a health or lifestyle diagnostic tool. Dr. Fatima Stanford, an obesity medicine specialist and the Equity Director of the Endocrine Division at Massachusetts General Hospital put it succinctly when she said "BMI does not come from science or medicine." Dr. Stanford and other experts have openly stated that BMI can be useful in tracking population-wide weight trends, but it falls short by failing to account for differences among the sexes and ethnic groups, and it can target some people, including athletes, as overweight or obese because it does not distinguish between muscle mass and fat. Unfortunately, BMI has become the standard “go-to” tool that determines who, when it comes to health consequences, is most at risk - and who qualifies for often-expensive treatments. Without using BMI as the principle tool, many studies have shown that people who are overweight or obese are at greater risk for a host of health problems, including diabetes, liver issues, osteoarthritis, high blood pressure, sleep apnea, and cardiovascular problems; this is beyond debate. The BMI measure is commonly included in the prescribing of weight loss drugs. Some of the newest and most effective drugs, such as Wegovy, limit use to patients who have a BMI of 30 or higher - the BMI obesity threshold - or the lower level of 27, but then only if the patient has at least one weight-related medical condition, such as diabetes. Doctors can prescribe medications to patients who don't meet those BMI requirements, but insurance companies in most cases will not cover the cost. While most insurers, including Medicare in the USA, cover some forms of bariatric surgery for weight loss, they may require a patient to have a BMI of at least 35, along with other health conditions, such as high blood pressure or diabetes, to qualify. With medications, it can be even trickier. Medicare, for example, does not cover most prescription weight loss drugs, although it will cover behavioral health treatments and obesity screening. Dr. Stanford says that "It's very frustrating because everything we do in obesity medicine is based on these cutoffs." Serena Nangia, communications director for Project Heal, a non-profit that helps patients get treatment, whether they are uninsured or have been denied care through their health plan said “For eating disorders, insurers often use BMI to make coverage decisions and can limit treatment to only those who rank as underweight, missing others who need help.” Serena went on to say "Because there's such a focus on BMI numbers, we are missing people who could have gotten help earlier, even if they are at a medium BMI. If they are not underweight, they are not taken seriously, and their behaviors are overlooked." DISCLAIMER: This video and description contain discount codes, which means that if you use the code, I will receive a small commission. FAIR-USE COPYRIGHT DISCLAIMER Copyright Disclaimer Under Section 107 of the Copyright Act 1976, allowance is made for "fair use" for purposes such as criticism, commenting, news reporting, teaching, scholarship, and research. Fair use is a use permitted by copyright statute that might otherwise be infringing. Non-profit, educational, or personal use tips the balance in favor of fair use. #BodyMassIndex #BMI #BMIChart

A new study into coffee and longevity has just been publishes, this study looks into ground coffee, Decaf and instant coffee. Renue by Science 10% Discount Code: MYNMN (https://renuebyscience.com/?rfsn=5692699.331801&coupon-code=MYNMN) Renue by Science 15% Subscription Service Discount Code: MYNMNSUB DoNotAge.org 10% Discount Code: MYNMN (https://bit.ly/2VBDgNt) I hope you enjoy my content and find it interesting or informative, if so, please consider supporting the channel by using one of the links below: *Buy me a Kofi: https://ko-fi.com/mynmnexperiment *Patreon: https://bit.ly/3hhfjl5 *SubscribeStar: https://bit.ly/3psYo23 My Current Anti-Aging Protocol: • 1.5 grams of NMN (https://bit.ly/3c2Fxt8) • 1.5 grams of Trans-resveratrol (Tue, Thu & Sat) (https://bit.ly/3yxeqy2) • 500mg Metformin • 1.5 grams of TMG (https://bit.ly/3oe1Ted) • 5,000 IU (International Units) of vitamin D3 (https://bit.ly/3P32hYH) • 120 mcg (micrograms) of vitamin K2 (Mk 7) (https://bit.ly/3PhkBgn) • 250mg Magnesium (L-Threonate) (https://bit.ly/3O4pZ5o) • 200mg high molecular weight hyaluronic acid (https://bit.ly/3P0Z4c2) • 2,400mg of Fisetin, on the 1st, 2nd & 3rd of each month (https://bit.ly/3P2rSB0) • 2,400mg of Quercetin, on the 1st, 2nd & 3rd of each month (https://bit.ly/3IzulAy) • 81mg of aspirin (https://bit.ly/3uFjtem) • 600mg DIM While the research doesn't claim that drinking more coffee adds years to your life (an increase in lifespan), it's nevertheless an intriguing association that scientists are keen to investigate further as it does point towards an uptick in healthspan. It's also important to weigh-up the findings against previous studies that link some brain shrinkage, and an increased risk of dementia, for those who consume more than 6 cups of coffee a day. Professor Peter Kistler of the Baker Heart & Diabetes Institute in Australia said "In this large, observational study, ground, instant and decaffeinated coffee were associated with equivalent reductions in the incidence of cardiovascular disease and death from cardiovascular disease or any cause. The results suggest that mild to moderate intake of ground, instant and decaffeinated coffee should be considered part of a healthy lifestyle." In this study, the sample provided an average of 12 and a half years' worth of health and dietary information on 449,563 people with a median age of 58. The UK Biobank is a large-scale database containing over half a million records on individuals' genetics and health, and lifestyle markers. The groups were split into types of coffee they usually drank; so ground coffee, instant coffee and decaffeinated - with just over 100,000 people reporting that they didn't drink coffee at all. As part of the analysis, the researchers also factored in confounding factors such as age, sex, ethnicity, obesity, high blood pressure, diabetes, obstructive sleep apnea, smoking status, and tea and alcohol consumption. The team computed the differences in heart health outcomes, and death from any cause, for all coffee drinkers over the study period of 12 and a half years, this was compared to those who didn't drink coffee. Drinking instant, ground and even decaffeinated coffee were all associated with a lower likelihood of death. Those who drank two or three cups of coffee a day had better odds of living longer than those who didn't drink any coffee at all. Professor Peter Kistler went on to say "Caffeine is the most well-known constituent in coffee, but the beverage contains more than 100 biologically active components. It is likely that the non-caffeinated compounds were responsible for the positive relationships observed between coffee drinking, cardiovascular disease and survival." Digging deeper, the team found coffee consumption was also linked with the development of cardiovascular disease, with the lowest risk seen amongst those who consumed two to three cups a day. There were slightly different findings associated with the risk of arrhythmia or an abnormal heart rhythm too, here ground and instant coffee, but not decaffeinated, were linked to a lower likelihood of developing the condition. Once again, just a couple of cups each day seemed to be the sweet spot. DISCLAIMER: This video and description contain discount codes, which means that if you use the code, I will receive a small commission. FAIR-USE COPYRIGHT DISCLAIMER Copyright Disclaimer Under Section 107 of the Copyright Act 1976, allowance is made for "fair use" for purposes such as criticism, commenting, news reporting, teaching, scholarship, and research. Fair use is a use permitted by copyright statute that might otherwise be infringing. Non-profit, educational, or personal use tips the balance in favor of fair use. Coffee health benefits, benefits of drinking black coffee, Coffee health risks, Coffee health problems, Coffee health effects, is black coffee good for health, is black coffee good for weight loss, is coffee good for you. #Coffee #Caffeine #decaf

This week’s giveaway is two bottles of their 90 (so 180) Liposomal Apigenin capsules, each capsule contains 30mg of liposomal Apigenin. As always this is 3rd party tested for purity and heavy meats and is produced in an FDA approved facility. Two containers would normally sell for $99.90 Renue by Science 10% Discount Code: MYNMN (https://renuebyscience.com/?rfsn=5692699.331801&coupon-code=MYNMN) Renue by Science 15% Subscription Service Discount Code: MYNMNSUB I hope you enjoy my content and find it interesting or informative, if so, please consider supporting the channel by using one of the links below: *Buy me a Kofi: https://ko-fi.com/mynmnexperiment *Patreon: https://bit.ly/3hhfjl5 *SubscribeStar: https://bit.ly/3psYo23 My Current Anti-Aging Protocol: • 1.5 grams of NMN (https://bit.ly/3c2Fxt8) • 1.5 grams of Trans-resveratrol (Tue, Thu & Sat) (https://bit.ly/3yxeqy2) • 500mg Metformin • 1.5 grams of TMG (https://bit.ly/3oe1Ted) • 5,000 IU (International Units) of vitamin D3 (https://bit.ly/3P32hYH) • 120 mcg (micrograms) of vitamin K2 (Mk 7) (https://bit.ly/3PhkBgn) • 250mg Magnesium (L-Threonate) (https://bit.ly/3O4pZ5o) • 200mg high molecular weight hyaluronic acid (https://bit.ly/3P0Z4c2) • 2,400mg of Fisetin, on the 1st, 2nd & 3rd of each month (https://bit.ly/3P2rSB0) • 2,400mg of Quercetin, on the 1st, 2nd & 3rd of each month (https://bit.ly/3IzulAy) • 81mg of aspirin (https://bit.ly/3uFjtem) • 600mg DIM DISCLAIMER: The Video Content has been made available for informational and educational purposes only. The video creator does not make any representation or warranties with respect to the accuracy, applicability, fitness, or completeness of the Video Content. The Video Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. The video creator hereby disclaims any and all liability to any party for any direct, indirect, implied, punitive, special, incidental or other consequential damages arising directly or indirectly from any use of the Video Content, which is provided as is, and without warranties. Best Apigenin brand in 2023, best Apigenin supplement 2023, best Apigenin supplements reviews, best Apigenin, best Apigenin supplement, best Apigenin supplement on the market, best Apigenin 2023, Apigenin Human Trial, Dr. David Sinclair,David Sinclair PhD,DoNotAge.org,DoNotAge,Renue by Science, Renue by Science reviews,Renue by Science Apigenin,ProHealth Longevity, ProHealth Longevity reviews,ProHealth longevity Apigenin,Apigenin, Apigenin Powder,Apigenin Supplement,Apigenin Capsules,Apigenin tablets,Cheapest Apigenin Supplement,where to buy Apigenin,Apigenin side effects,Apigenin Supplement Review. DISCLAIMER: This video and description contain discount codes, which means that if you use the code, I will receive a small commission. FAIR-USE COPYRIGHT DISCLAIMER Copyright Disclaimer Under Section 107 of the Copyright Act 1976, allowance is made for "fair use" for purposes such as criticism, commenting, news reporting, teaching, scholarship, and research. Fair use is a use permitted by copyright statute that might otherwise be infringing. Non-profit, educational, or personal use tips the balance in favor of fair use. #livelonger #livelong #Aging #Lifespan #healthspan #weightloss #nutrition #fat #drdavidsinclair #immortal #aging #antiaging #NAD #wellness #healthylifestyle #healthyliving #healthy #antiaging #biohacking #healthylife #intermittentfasting #paleo #healing #selfcare #mindset #organic #wellbeing #epigenetics #guthealth #holistic #detox #functionalmedicine

The benefits of resistance training for Longevity are well documented, but what type of resistance training is right for you? Renue by Science 10% Discount Code: MYNMN (https://renuebyscience.com/?rfsn=5692699.331801&coupon-code=MYNMN) Renue by Science 15% Subscription Service Discount Code: MYNMNSUB DoNotAge.org 10% Discount Code: MYNMN (https://bit.ly/2VBDgNt) I hope you enjoy my content and find it interesting or informative, if so, please consider supporting the channel by using one of the links below: *Buy me a Kofi: https://ko-fi.com/mynmnexperiment *Patreon: https://bit.ly/3hhfjl5 *SubscribeStar: https://bit.ly/3psYo23 My Current Anti-Aging Protocol: • 1.5 grams of NMN (https://bit.ly/3c2Fxt8) • 1.5 grams of Trans-resveratrol (Tue, Thu & Sat) (https://bit.ly/3yxeqy2) • 500mg Metformin • 1.5 grams of TMG (https://bit.ly/3oe1Ted) • 5,000 IU (International Units) of vitamin D3 (https://bit.ly/3P32hYH) • 120 mcg (micrograms) of vitamin K2 (Mk 7) (https://bit.ly/3PhkBgn) • 250mg Magnesium (L-Threonate) (https://bit.ly/3O4pZ5o) • 200mg high molecular weight hyaluronic acid (https://bit.ly/3P0Z4c2) • 2,400mg of Fisetin, on the 1st, 2nd & 3rd of each month (https://bit.ly/3P2rSB0) • 2,400mg of Quercetin, on the 1st, 2nd & 3rd of each month (https://bit.ly/3IzulAy) • 81mg of aspirin (https://bit.ly/3uFjtem) • 600mg DIM Let’s assume either you don’t lift weights as part of your exercise or longevity regime, or you do lift weights - but you aren’t sure if you are doing it correctly; correctly as in the type of weight lifting you need to do to achieve a specific goal. Part of your research may include checking videos on YouTube or influencers on Instagram, but as with most things that don’t have a clear-cut answer; and you may end up becoming confused and even hesitant to want to look any deeper, don’t worry - you’re not alone. The author of this piece Dr. Mandy Hagstrom is an exercise scientist at the University Of New South Wales and former national Olympic weightlifting champion, who now researches resistance training, also known as lifting weights. She says that research suggests lifting smaller weights and doing more repetitions (or, in gym parlance, "Reps") can have a role to play - but it all depends on your goals. In short: if your goal is to build serious strength and bone density, lifting heavy is an efficient way to do it. But if you can't lift heavy, or it's not your thing, don't think lifting lighter weights is a complete waste of time, it’s not! As we age the density of our bones reduces, this leaves us open to developing diseases such as Osteoporosis. Osteoporosis is a health condition that weakens the bones, making them fragile and more likely to break. It develops slowly over several years and is often only diagnosed when a fall or sudden impact causes a bone to actually break. Weight or resistance training is a way to increase bone density and fend off Osteoporosis. What's heavy for one person may be a piece of cake for another, so how do you work out what is “heavy” for you? In resistance training, the load or "heaviness" of a weight is often expressed as a percentage of a your “repetition maximum" (frequently shortened to "1RM" or 1 Rep Max). A one Rep Max is the heaviest weight you are able to successfully lift once, so you are too weak to do it twice - Around 80% of your one 1Rep Max often defined as "high intensity" or heavy lifting. This would be different depending on the muscle groups used, exercises using larger muscle groups such as the chest when bench pressing will have a higher 1 Rep Max that bicep curls, because your biceps are small in comparison to your chest. Around 40% or less of your 1 Rep Max is often defined as "low intensity". In other words, lifting 80% of your one repetition maximum would allow you to do about eight reps. Some estimates predict you could do approximately 20 reps at 60% of your 1 Rep Max (of course, this varies slightly depending on the person). It's worth remembering not everyone can lift heavy, maybe due to age, or an injury, or just being new to resistance training. Remember nobody, not even Arnold Schwarzenegger “crushed it” the first day he went to the gym, although you may not be able to lift heavy now, it doesn't mean that will always be the case. DISCLAIMER: This video and description contain discount codes, which means that if you use the code, I will receive a small commission. FAIR-USE COPYRIGHT DISCLAIMER Copyright Disclaimer Under Section 107 of the Copyright Act 1976, allowance is made for "fair use" for purposes such as criticism, commenting, news reporting, teaching, scholarship, and research. Fair use is a use permitted by copyright statute that might otherwise be infringing. Non-profit, educational, or personal use tips the balance in favor of fair use. #FitOver40 #SeniorFitness #FitOver50

a new study out of the University of California, Berkley has come up with 4 key things that will allow you to sleep better and wake up more refreshed. Renue by Science 10% Discount Code: MYNMN (https://renuebyscience.com/?rfsn=5692699.331801&coupon-code=MYNMN) Renue by Science 15% Subscription Service Discount Code: MYNMNSUB DoNotAge.org 10% Discount Code: MYNMN (https://bit.ly/2VBDgNt) I hope you enjoy my content and find it interesting or informative, if so, please consider supporting the channel by using one of the links below: *Buy me a Kofi: https://ko-fi.com/mynmnexperiment *Patreon: https://bit.ly/3hhfjl5 *SubscribeStar: https://bit.ly/3psYo23 My Current Anti-Aging Protocol: • 1.5 grams of NMN (https://bit.ly/3c2Fxt8) • 1.5 grams of Trans-resveratrol (Tue, Thu & Sat) (https://bit.ly/3yxeqy2) • 500mg Metformin • 1.5 grams of TMG (https://bit.ly/3oe1Ted) • 5,000 IU (International Units) of vitamin D3 (https://bit.ly/3P32hYH) • 120 mcg (micrograms) of vitamin K2 (Mk 7) (https://bit.ly/3PhkBgn) • 250mg Magnesium (L-Threonate) (https://bit.ly/3O4pZ5o) • 200mg high molecular weight hyaluronic acid (https://bit.ly/3P0Z4c2) • 2,400mg of Fisetin, on the 1st, 2nd & 3rd of each month (https://bit.ly/3P2rSB0) • 2,400mg of Quercetin, on the 1st, 2nd & 3rd of each month (https://bit.ly/3IzulAy) • 81mg of aspirin (https://bit.ly/3uFjtem) • 600mg DIM Links: https://www.nature.com/articles/s41467-022-34503-2 https://www.sciencedaily.com/releases/2022/11/221129143811.htm https://www.sciencealert.com/oversleeping-is-not-bad-for-you-according-to-experts-but-don-t-make-it-a-habit https://www.sciencealert.com/being-tired-or-fatigued-is-common-but-here-s-when-you-should-worry https://www.sciencealert.com/most-of-us-hit-snooze-but-what-is-it-actually-doing-to-us https://www.sciencedirect.com/science/article/abs/pii/S0149763418309175?via%3Dihub This new study identified four key factors that make a difference in waking up well in the morning – powering through to lunchtime alert and refreshed at one end of the scale, or fighting through grogginess and multiple taps of the snooze button at the other. The team behind the study said these factors, independent of the genetics that we are all born with, can all be modified - to some extent - to ensure we get off to a better start in the mornings, and ultimately set ourselves up for a successful day. The team of researchers led by neuroscientist and sleep researcher Raphael Vallat of the University of California, in their published paper, asked the questions: "Why is it that we human beings fluctuate in our alertness from one day to the next?" and "Why do we wake one morning feeling alert, yet another morning, flounder in that level of alertness upon awakening?" A total of 833 people participated in the study, most of whom were twins (this helped the researchers filter out variations due to genetics). Over two weeks they recorded their food intake, their physical activity, their sleep patterns and their glucose levels. The volunteers also rated their alertness at several points throughout the day. The researchers looked at sleep duration, timing, and efficiency of sleep overnight. Overall sleeping longer and waking up later than normal were both associated with better morning alertness. My comment there is that they slept longer than normal and woke up later than normal; does this mean that their normal sleep patterns before the study were sub-optimal? What was their normal? Higher levels of movement in the day (as well as strangely, less physical activity at night) were associated with more continuous and less disrupted sleep, which in turn predicted increased alertness from the participants in the morning. Although not surprising, good to know, and another reason to keep exercising as we age. But, they say less activity at night, this may be difficult to achieve for those who can only exercise at night. Morning meals with more carbohydrates led to better alertness levels, while more protein had the opposite effect. By keeping the calories in the supplied meals the same, the researchers could focus on the nutritional content of what was being eaten. Again, more Carbs leading to better alertness is not surprising, but what about the inevitable crash as insulin spikes? Lastly, a surge in blood sugar levels after breakfast – this was tested using a pure glucose liquid drink and was associated with reduced alertness. DISCLAIMER: This video and description contain discount codes, which means that if you use the code, I will receive a small commission. FAIR-USE COPYRIGHT DISCLAIMER Copyright Disclaimer Under Section 107 of the Copyright Act 1976, allowance is made for "fair use" for purposes such as criticism, commenting, news reporting, teaching, scholarship, and research. Fair use is a use permitted by copyright statute that might otherwise be infringing. Non-profit, educational, or personal use tips the balance in favor of fair use. #Sleep #Sleepy #Insomnia